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Featured Genetics Open Neuroscience Articles

·December 2, 2015·6 min read

Fountain of Youth: Tweaking Genes to Extend Lifespan

Researchers have identified genes implicated in physical aging and discovered that influencing just one of the genes can extend the healthy lifespan of animals.

Stained glioblastoma brain slice is shown.

Brain Cancer Featured Neurology Open Neuroscience Articles

·November 16, 2015·5 min read

Making Resistant Brain Cancer Cells Sensitive to Treatment

Researchers have discovered a way in which to sensitize drug-resistant human glioblastoma cells to chemotherapy.

Featured Genetics

·October 12, 2015·4 min read

Mapping Genes That Increase Lifespan

Researchers have identified over 230 genes which, when deleted, increase the replicative life span of yeast cells. 189 of these genes have been linked to aging and the researchers believe the results could provide new genomic targets that could be used to improve human health.

The image is comparison of a dendrite with the protein NrCAM (top) and a dendrite without the protein (bottom).

Autism Featured Genetics

·September 19, 2014·3 min read

Researchers Link Gene to Increased Dendritic Spines; A Signpost of Autism

A new study reports by deleting the NrCAM gene, researchers believe they have found a potential way to prune back the neural connections implicated in ASD.

This image is a neuron from the brain of a young person with autism.

Autism Electrophysiology Featured

·August 21, 2014·5 min read

Children with Autism Have Extra Synapses in Brain

According to a new study, children with autism have an excess of synapses in the brain, due to a slowdown of the normal pruning process during development.

Brain Cancer Featured Neurology

·December 18, 2013·6 min read

Recurrent Brain Cancers Follow Distinctive Genetic Paths

Recurrent gliomas could have genetic profiles which are different from those of the initial tumors that spawned them, a new study reports.

Featured Genetics

·November 14, 2013·4 min read

FDA Approved Immune-Modulating Drug Unexpectedly Benefits Mice With Fatal Mitochondrial Defect

Rapamycin, a transplant anti-rejection drug, enhances survival and reduces the disease progression in a mouse model of Leigh's syndrome, a new study reports.

This is an MRI scan of a brain with a glioma.

Brain Cancer Featured

·November 7, 2013·3 min read

Common Genetic Pathway Could be Conduit to Pediatric Tumor Treatment

Researchers discover the mTOR pathway is highly active in many cases of pediatric low-grade glioma. Blocking the pathway lead to a decreased growth of the brain tumors.

The image shows an electrophysiology slide of the mTORC1 activation

Featured Neurology Open Neuroscience Articles

·October 22, 2013·2 min read

Study Points to Possible Treatment for Brain Disorders

Researchers investigate how neurons are generated in hope to find potential new treatments for TSC and other neurological disorders.

The image shows an MRI scan of a glioblastoma multiforme in a human brain.

Brain Cancer Featured

·February 26, 2013·3 min read

Novel Combination Therapy Shuts Down Escape Route, Killing Glioblastoma Tumor Cells

A new study discovers molecular pathways that could lead to new targeted therapies which may potentially treat Glioblastoma, the most common and lethal form of brain cancer in adults.

Featured Neurology

·September 19, 2012·4 min read

Scientists Show Biological Mechanism Can Trigger Epileptic Seizures

Researchers at Cincinnati Children’s Hospital Medical Center report that molecular disruptions in small neurons called granule cells – located in the dentate gyrus region of the brain – caused brain seizures in mice similar to those seen in human temporal lobe epilepsy.

Featured Genetics Neurology

·September 13, 2012·3 min read

Neural Stem Cells Regenerate Axons in Severe Spinal Cord Injury

Researchers were able to regenerate an astonishing degree of axonal growth at the site of severe spinal cord injury in rats. Results were then replicated using two human stem cell lines, one already in human trials for ALS. “We obtained the exact results using human cells as we had in the rat cells,” said Tuszynski.

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