Reducing levels of the Alzheimer's related Tau protein prevents autism-like behaviors in mouse models. Tau reduction also prevented seizures in the animals. Read More
Genetically silencing mTORC2 in mouse models prolonged lifespan, suppressed seizures, increased long-term memory, and reduced autism-like behaviors. Read More
Exploring the effects of 17 different lifespan-extending interventions on gene activity, researchers identified genetic biomarkers for longevity in mice. Read More
A new study clarifies the mechanism behind how ketamine works as an antidepressant. Researchers say there is evidence to suggest ketamine binds to NMDA receptors, instead of opioid receptors. Reducing the belief that ketamine is an opioid may make patients with depression more open to using the treatment. Read More
TRPML1 may contribute to the neuroprotective and anti-aging properties of rapamycin. Read More
Study implicates disrupted autophagy and protein aggregation in the pathogenesis of autism schizophrenia and social behavior deficits in other disorders. Read More
Combining carboplatin, a common chemotherapy drug, with everolimus, a drug that blocks mTOR, is effective at inducing apoptosis and slowing tumor growth in patients with pediatric low-grade glioma brain cancer. Read More
Researchers say the sight and smell of food alone may be enough to prompt the liver to start the processes that help digest food. Read More
A new study reports the Ketogenic diet can help to improve cognition. The study reports the Ketogenic diet can help improve balance in the gut microbiome, lower blood glucose levels and increase the processes that help to clear amyloid beta from the brain. Read More
A new study reveals psychedelics increase dendrites, dendritic spines and synapses, while ketamine may promote neuroplasticity. The findings could help develop new treatments for anxiety, depression and other related disorders. Read More
Researchers have derived purkinje cells from patients with TSC, a genetic syndrome that includes some ASD-like symptoms. The cells, researchers say, have several characteristics that could help explain how ASD develops at the molecular level. Read More
ZNF804A, a gene that contributes to schizophrenia also affects brain function and structure during early stages of fetal development, researchers report. Read More
