UC Berkeley researchers report they have successfully used CRISPR-Cas9 gene editing to delay symptoms and extend lifespan in mouse models of ALS.
University of Pennsylvania researchers use cryptographic techniques to decode the activity of motor neurons.
Targeting autophagy may help in the battle against ALS and other diseases that affect motor neurons, researchers report.
Researchers have generated motor neurons from people with familial ALS who carry FUS mutations.
A groundbreaking study from Karolinska Institute researchers reports astrocytes play a key tole in the respiratory center of the brain stem and assist with the regulation of breathing. The findings are significant as they could provide clues to the causes of respiratory diseases.
In early stages of ALS, autophagy helps to suppress disease progression, but accelerates the spread as the disease enters into later stages, researchers report.
WUSTL researchers have converted skin cells into motor neurons without going through the stem cell state. The new technique could help in the development of devastating neurodegenerative diseases, like ALS, that affect motor neurons.
Researchers report memories that trigger PTSD and anxiety can be erased without affecting other memories.
A new study sheds light on how some forms of motor neuron disease begins and progresses at a cellular level.
Study implicates abnormalities in SOD1 with Parkinson's disease and ALS.
Researchers implicate a variant in the UBQLN4 gene as a possible cause of ALS. The variant disrupts cellular processes that drive motor neuron development.
Findings enhance understanding how the brain controls movement.