A new study finds slowdowns in the transport and delivery of proteins, nutrients and signaling molecules within nerve cells could contribute to the development of ALS. Read More
Researchers combined intact neurons from a rat's spinal cord with a tissue-engineered 3D muscle system, creating a biohybrid robot, or biobot. After culturing the system for seven days, the motor neurons from the spinal cord produced electrical activity, causing contractions in the artificial muscles and mimicking the behavior of the peripheral nervous system. The findings could have positive implications for the treatment of neurodegenerative disorders that affect motor control. Read More
Findings enhance understanding how the brain controls movement. Read More
A new study sheds light on how a single neuron can perform multiple functions in a model organism. Read More
Researchers have generated motor neurons from people with familial ALS who carry FUS mutations. Read More
A new study reveals some brain systems in a dish, dubbed circuitoids, exhibit coordinated and spontaneous rhythmic activity that can drive repetitive movements. Read More
Researchers report malfunctioning astrocytes could contribute to neurodegenerative diseases, such as ALS. Read More
A new study uncovers molecular changes which may explain why motor neurons, rather than other neurons, are affected by the childhood illness, SMA. Read More
The TBK1 gene regulates the disease progression of ALS in mouse models of the neurodegenerative disease. Loss of the TBK1 gene in motor neurons increases SOD1 aggregation and accelerates the onset of the disease. Read More
Researchers have discovered a potential treatment that may help delay motor neuron loss in ALS. Read More
Researchers identify Neurexin2 as a new target for potential treatment of spinal muscular atrophy. Read More
Performing post-mortem staging of the brains and spinal cord tissue of patients with ALS, researchers discover the neurodegenerative disease could progress from one start point in the CNS to other regions of the brain and spinal cord. Read More
