Findings could have implications for new avenues of research for a range of neurodegenerative diseases including ALS and Alzheimer's.
Using MEG neuroimaging, researchers have identified a new marker that can be used to predict the clinical outcomes for those suffering from ALS.
Motor system neurons not only control movement, they also incite action.
Mutations in the IL18RAP gene reduce inflammation and appears to protect the brain against ALS.
PolyP, an inorganic polyphosphate released by astrocytes in people with ALS and frontotemporal dementia contributes to the signature motor neuron death associated with the disease pathologies.
Study reveals how miniature release events help to keep neurons intact and preserve motor neuron function in aging insects.
Cedars-Sinai has been awarded $11.99 million by California's stem cell agency to launch a clinical trial testing a potential gene and stem cell therapy for amyotrophic lateral sclerosis (ALS).
Using single nucleus RNA sequencing, researchers have mapped 21 subtypes of motor neurons in the spinal cords of mice.
Some neurons have the ability to detect and compensate for neighboring neurons, while others do not. The findings shed new light on synaptic plasticity.
A new study challenges the popular theory of intrinsic, dynamic patterns control motor behaviors. Researchers found neuron population dynamics in the motor cortex are different during reaching and grasping behaviors.
A defective protein quality control system leads to motor neuron death associated with disorders like ALS.
Study reveals a self-corrective mechanism within synapses that is activated by neurodegeneration and slows disease progression in animal models of ALS.
