The STARD7 enzyme helps transport the antioxidant coenzyme Q from the mitochondria to the cell surface.
Human cells with impaired mitochondria expend more energy. While this hypermetabolism enhances a cell's short-term survival, it also dramatically increases the rate at which the cell ages.
Findings reveal a cellular mechanism that helps improve physical fitness through exercise training and identifies one anti-aging intervention that helps delay the declines that occur with natural aging.
Astrocytes enhance healing following a brain hemorrhage by transferring their mitochondria to damaged neurons.
Cannabinol, an active ingredient in cannabis, can help protect brain cells from oxidative damage and preserve mitochondrial function.
People with untreated depression have lower levels of mitochondrial proteins. For those who responded to the SSRI antidepressants, the proteins returned to a normal level, but showed no increase in those who did not respond to medication.
Post-mortem studies of brain tissue from ALS patients reveal an abnormal form of tau is present in novel brain areas, and the tau interacts with DRP1. The tau appears to cause the brain cell's mitochondria to fragment and increase oxidative stress. Reducing tau reversed the effect, decreasing oxidative stress and mitochondrial fragmentation.