Researchers link new protein to Parkinson’s
The MITOL protein has been implicated in Parkinson's disease. ... Read More...
mitochondria
Miro2 is a Parkin receptor for selective removal of damaged mitochondria
Findings from a mouse model study reveal Miro2 functions as a platform for Parkin translocation and damaged mitochondrial clearance. ... Read More...
Neurodevelopmental disorders may be rooted in genetics and mitochondrial deficits: Mouse study
Mouse models of DiGeorge/22q1 Deletion Syndrome reveal a connection between mitochondrial dysfunction, deficits in cortical connectivity and cognitive impairments. Function was restored through antioxidant therapy.... Read More...
Mitochondrial function may explain link between intelligence, health and aging
Mitochondrial function may help explain the link between intelligence, general health and aging. ... Read More...
Cell death may be triggered by ‘hit-and-run’ interaction
Two different parts to the BAX protein can bind to BH3-only, and these sites function at different stages of BAX activation. When BH3-only binds to one of the regions, BAX becomes able to damage mitochondria. ... Read More...
New insights into proteins key to Charcot-Marie-Tooth and other nerve diseases
Increasing levels of the MFN1 protein counterbalances mutated MFN2, reducing symptoms associated with Charcot-Marie-Tooth disease and neurodegeneration in mouse models.... Read More...
Researchers Describe First Model of Mitochondrial Epilepsy
Researchers have developed a new model of mitochondrial epilepsy which captures specific features observed in patients. The new model may help provide better therapies and treatments for the condition.... Read More...
‘Lack of Cleaning’ in Brain Cells is Central to Alzheimer’s
Researchers report dysfunctional mitophagy may contribute to the development of Alzheimer's disease. When mitophagy is improved, symptoms of Alzheimer's almost disappeared in animal models of the disease. ... Read More...
Anxiety and Depressive Disorders Alter Brain Gene Activity
Researchers depression and anxiety alters energy metabolism in the brain.... Read More...
The Mysteries of the Super-Ager Revealed
Scientific research is helping to unlock the secrets behind why some people live to become super-agers. Researchers propose ways in which we can slow the aging process and extend our life spans.... Read More...
Shedding Light on the Evolution of Metabolism
Researchers report the ability to use sugar as food varies strongly between closely related species. The study identifies a genetic basis for this variation and could shed light on how human populations with different dietary histories may respond differently to modern, sugar rich diets. ... Read More...
Caffeine From Four Cups of Coffee Protects the Heart With the Help of Mitochondria
A new study reports caffeine concentration, the equivalent of four cups of coffee, can promote the movement of a regulatory protein into mitochondria. This can enhance mitochondrial function and protect heart cells from damage.... Read More...