Latest

metabolism

Featured Neurology Open Neuroscience Articles

·September 23, 2020·3 min read

Fructose Made in the Brain Could Be a Mechanism Driving Alzheimer’s

Alzheimer's disease may be driven by excessive fructose metabolism in the brain. The findings shed light on why diseases, such as diabetes and obesity, are linked to an increased risk of Alzheimer's.

This is a painting of a depressed person

Featured Neuroscience Psychology

·September 15, 2020·3 min read

Depression, Not Anxiety, Linked With Inflammation and Metabolic Change

Depression and anxiety have different biochemical links to inflammation and lipid metabolism. Those with depression have greater levels of inflammation and different types and amounts of lipids in their blood compared to those with anxiety. The metabolites associated with depression were linked to the severity of symptoms. Higher levels of lipids associated with depression detected in a person's blood correlated with more severe symptoms.

Featured Neurology Neuroscience Open Neuroscience Articles

·August 31, 2020·3 min read

Neurons Protect Themselves From Degeneration by Adapting Their Metabolism

Neurons can counteract degeneration and promote survival by adapting their metabolism.

Featured Genetics

·August 14, 2020·7 min read

Loss of a Specific Enzyme Boosts Fat Metabolism and Exercise Endurance

The enzyme PHD3 plays a critical role in sensing nutrient availability and regulating the ability of muscles to break down fat. Blocking PHD3 production in mice leads to dramatic improvements in specific measures of fitness. Findings shed light on the key mechanism for how cells metabolize fuel and provide a novel understanding of muscle function and fitness.

Featured Neuroscience Open Neuroscience Articles

·August 12, 2020·3 min read

Exercise Makes Female Rats Hungrier and Sustains Weight Gain

Study in rats reveals sex differences may play a key role in the effectiveness of exercise as an appetite regulator. Exercising female rats ate more than those who did not partake in physical activity. The same effect was not seen in males.

Featured Neuroscience

·August 11, 2020·4 min read

Excess Weight Among Pregnant Women May Interfere With Child’s Developing Brain

Maternal obesity may hinder their child's brain development as soon as the second trimester of pregnancy. High maternal BMI is associated with changes to the child's prefrontal cortex and anterior insula, two brain areas associated with decision making, and behavior.

Featured Neuroscience Open Neuroscience Articles

·August 6, 2020·4 min read

REM Sleep Tunes Eating Behavior

Suppressing the activity of hypothalamic neurons in mice during REM sleep resulted in a decrease in the amount of food later consumed. The study suggests REM sleep is essential to stabilize food intake.

This is a cartoon of a doctor measuring a belly

Featured Neuroscience

·August 5, 2020·3 min read

Scientists Discover the Switch That Makes Human Brown Fat Burn Energy

Beta2-adrenergic receptors in brown fat cells are responsible for stimulating thermogenesis.

This shows a woman and a brain in a lightbulb

Electrophysiology Featured Neuroscience

·August 3, 2020·5 min read

Energy Demands Limit Our Brains’ Information Processing Capacity

Paying attention alters how the brain allocates its limited energy. As the brain uses more energy to process information we attend to, the less energy is supplied to processing outside our field of attention.

Featured Neuroscience

·July 31, 2020·3 min read

Timing of Meals Affects Body Rhythms and Metabolic Health

Both food timing and the integrity of the internal clock in the liver altered rhythms of metabolism in mice. Almost half of the rhythmic genes are regulated by both the internal clock and when food is ingested.

Featured Neurology

·July 14, 2020·4 min read

Link Between Delirium and Brain Energy Disruption Discovered

Artificially inducing peripheral inflammation in mice triggered the sudden onset of delirium-like cognitive dysfunction, and this was mediated by a disturbance in energy metabolism.