What comes first, beta-amyloid plaques or thinking and memory problems?
Subtle changes in thinking and memory may appear before, or in conjunction with, the development of amyloid plaques.... Read More...
memory loss
Drugs that quell brain inflammation reverse dementia
Older mice given anti-inflammatory medication were better able to learn new tasks and became almost as adept at learning as mice half their age.... Read More...
Research reveals no link between statins and memory loss
Study reveals there is no link between memory decline and statin use in older adults. Additionally, no association was found between statin use and cognitive decline in those with genetic risk factors for dementia.... Read More...
Vitamin B12 deficiency: what is Pernicious anemia, and why can it be so dangerous?
Pernicious anemia is an autoimmune disorder associated with vitamin B12 deficiency. The condition not only affects physical health, it also has a detrimental effect on the mental health of many who suffer from the condition.... Read More...
Critical role of brain circuits in improving learning and memory revealed
A newly identified neural network in the hippocampal formation plays a critical role in memory and object-location learning. The findings are highly relevant to learning and memory disorders, including Alzheimer's disease.... Read More...
Calcium is key to age-related memory loss
Mouse study reveals a clear correlation between cognitive ability in aging and presynaptic calcium levels.... Read More...
Can computer use, crafts and games slow or prevent age-related memory loss?
Middle-aged and older people who stay mentally active have a lower risk of developing mild cognitive impairment.... Read More...
Brain on Fire: Puzzling brain disease could now be better diagnosed and treated
A rare autoimmune disorder popularized by the autobiography and movie "Brain on Fire" is triggered by an attack on NMDA receptors. The disease occurs when antibodies attack NMDA receptors in the brain, leading to memory loss, intellectual changes, seizures, and death. ... Read More...
Blocking protein curbs memory loss in old mice
Blocking VCAM1 increased neurogenesis, and reduced microglia reactivity in the hippocampus of older mice. ... Read More...
Restoring brain function in mice with symptoms of Alzheimer’s disease
Senolytic drugs administered to mice reduced senescent cells around amyloid plaques by more than 90% and decreased neuroinflammation by 50%. Mice treated with the drug combination also showed improvements in spatial memory, compared to other Alzheimer's model mice who received no treatment. The findings could have positive implications for the treatment of Alzheimer's disease in people with the condition.... Read More...
Sugar entering the brain during septic shock causes memory loss
During sepsis, the body sheds fragments of heparan sulfate, which crossed the blood-brain barrier and enters the hippocampus. The presence of heparan sulfate in the hippocampus may cause memory loss associated with septic shock.... Read More...
Brain stimulation reverses age-related memory loss
Transcranial magnetic stimulation applied to the parietal lobe improves the function of brain areas important for memory which are disrupted by aging. The study reports TMS helps improve memory in older adults experiencing memory loss to the level of younger adults.... Read More...