A 20 year study finds regular exercise during mid-life appears to be a key protector against memory decline in later years.
Cognitive enhancement drugs do not help improve cognition or function in the long term for patients with mild cognitive impairment, a new study shows.
WUSTL researchers report a poor night's sleep can cause levels of amyloid beta to rise faster than the brain's waste disposal system can remove it. Researchers note frequent sleep disruptions can lead to an increased risk of developing Alzheimer's disease.
Researchers report histamines can help improve memory of objects up-to 25 days longer than normal in mice, as well as improving people's long term memory test scores. The study suggests taking histamines may help alleviate symptoms of memory disorders such as Alzheimer's and other dementias.
Researchers report amnesia caused by cannabinoids relies on the activation of the CB1 receptor in mitochondria in the hippocampus.
Senolytic drugs administered to mice reduced senescent cells around amyloid plaques by more than 90% and decreased neuroinflammation by 50%. Mice treated with the drug combination also showed improvements in spatial memory, compared to other Alzheimer's model mice who received no treatment. The findings could have positive implications for the treatment of Alzheimer's disease in people with the condition.
Researchers report a complex series of other molecular, cellular, circuit and network-level changes contribute to the progression of Alzheimer's disease.
Scientists have discovered that significantly more neurons are generated in the brains of older animals if the signaling molecule Dickkopf-1 is turned off. The results give rise to the question whether the function of Dickkopf-1 may be turned off using drugs to prevent age related cognitive decline.
Researchers report practicing simple meditation and listening to music can have benefits for those with preclinical memory loss.
Study reports success in treating cognitive decline and memory loss associated with Alzheimer's disease with the aid of personalized precision medicine.
Middle-aged and older people who stay mentally active have a lower risk of developing mild cognitive impairment.