MDD

·July 15, 2020

Early Life Stress Associated with Youth Onset of Depression for Some Types of Stress But Not Others

Examining the impact of eight types of early life stress on the onset of youth-onset depression, researchers found some had little impact on the development of the psychological disorder. Emotional abuse was more strongly associated with the development of major depressive disorder than other early stressors, such as poverty. Read More

Featured Neuroscience Psychology

·July 7, 2020

Brain Structural Elements in Psychiatric Disorders

Comparing data from multiple neuroimaging studies, researchers found shared brain structural abnormalities between four psychiatric disorders, including schizophrenia and bipolar disorder. They also identified brain signatures unique to each condition. Read More

Featured Neuroscience Psychology

·June 16, 2020

The molecular mechanisms of depression

Study reveals how the brain's opioid system is linked to mood changes associated with depression and anxiety. Neuroimaging revealed, in those with depression, there is a decreased number of opioid receptors in specific areas of the brain. Read More

Featured Genetics Neuroscience Psychology

·June 11, 2020

Adult stem cell study shows fish oil may help with depression

Using patient-derived adult stem cells, researchers found fish oil created an antidepressant response. Read More

Featured Neuroscience Psychology

·April 23, 2020

Natural mood regulation low or even absent in people with depression

During periods where personal choices of activities are constrained, natural mood regulation becomes impaired, resulting in an increased risk of depression. Read More

Featured Neuroscience Open Neuroscience Articles Psychology

·March 20, 2020

New drug can ease the side effects of medication against severe depression

A new substance named Lu AF60097 may help reduce side effects from tricyclic antidepressants in those with severe depression. Read More

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·March 9, 2020

The largest genetic map of psychiatric disorders so far

The largest genetic map of mental health disorders to date reveals there are three groups of highly genetically related disorders among eight psychiatric disorders. A gene related to nervous system development is a risk factor for all eight disorders studied. The RBFOX1 gene is implicated in seven of the eight disorders. ADHD and depression share 44% of genetic risk factors common in the general population. 109 pleiotropic loci affect more than one disorder. These pleiotropic loci are within genes that show heightened expression in the brain through the lifespan, beginning during the second trimester of pregnancy. Read More

Featured Neuroscience Psychology

·February 20, 2020

Decision time predicts the risk of depression relapse

Findings reveal it is possible to predict the risk of a person with MDD lapsing back into depression after stopping antidepressants. Those who relapse take longer to decide how much effort to invest for a reward. Read More

Featured Neuroscience Open Neuroscience Articles Psychology

·February 7, 2020

New biochemical ‘warning sign’ of early-stage depression identified

High levels of anthranilic acid in the blood may be a new biomarker for assessing the risk of developing major depressive disorder. Read More

Featured Neuroscience Open Neuroscience Articles Psychology

·December 26, 2019

Early-life exposure to dogs may lessen risk of developing schizophrenia

Exposure to household pet dogs in the early years of life was associated with a significantly decreased risk of being diagnosed with schizophrenia later in life. Read More

This shows a depressed looking woman sitting by a christmas tree

Featured Neuroscience Open Neuroscience Articles Psychology

·December 16, 2019

Want to avoid the holiday blues? Skip the sweet treats

If you are prone to depression, a new study suggests you should avoid indulging on dietary sugars. Added sugars have a pro-inflammatory effect on depressive disorders. Read More