According to a new study, experimentally increasing the activity of a subclass of nerve cells that produce GABA has an antidepressant effect in mice.
Researchers report ketamine's antidepressive effects require activation of opioid receptors in the brain. The study highlights the interaction between depression, pain and opioid addiction.
Minocycline, a broad-spectrum tetracycline antibiotic, has shown promise in the treatment of depression. Researchers say the antibiotic could help reduce brain inflammation associated with some cases of major depressive disorder. A small study conducted by researchers at Deakin University found those treated with Minocycline reported improved quality of life, reduced anxiety symptoms and a better global impression of their depression.
Nitrous oxide, a common anesthesia most often associated with dental procedures, may have a new purpose. Researchers found a single inhalation of 25% nitrous oxide gas was effective at alleviating symptoms of depression in those with a treatment-resistant form of the mental health disorder.
Researchers have identified the role Klf9 plays in the brain's response to stress. The study reports elevated levels of the protein were discovered in the hippocampus of women with MDD who faced stressful events.
A new study of 9/11 first responders helps confirm the link between cognitive impairment and PTSD.
Those with anxiety and depressive disorders may actively resist relaxation, especially if they are more sensitive to shifts in negative emotions.
Researchers are utilizing neuroimaging data to identify brain patterns and predict depression with the help of machine learning.