Nitrous oxide, a common anesthesia most often associated with dental procedures, may have a new purpose. Researchers found a single inhalation of 25% nitrous oxide gas was effective at alleviating symptoms of depression in those with a treatment-resistant form of the mental health disorder.
DNA markers in cells of patients with major depressive disorder appear to be two years older than markers in cells of people without the mental health disorder.
Researchers found that while there are genetic overlaps between the sexes in relation to mental health disorders, there are also sex-specific differences in how genes related to the immune system, central nervous system, and blood vessels affect people with mental health problems.
Differences in the expression of gene transcripts shed light on how mental health disorders with shared genetic risk factors differ in onset, symptoms, course of progression, and treatment responses.
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Using data from neuroimaging, a machine learning algorithm has identified key functional neural connections that could serve as a biomarker in the diagnosis of major depressive disorder.
Two doses of psilocybin in combination with therapy rapidly and significantly reduces symptoms in those with major depressive disorder. The effects appear to last for up to four weeks.
Sleep disturbances may be an outcome of Alzheimer's in those with a genetic predisposition, but not a cause of dementia. Those with genetic risk factors for Alzheimer's tend to have shorter sleep durations and are more likely to be early risers but are less likely to suffer from insomnia.
Study reports that almost 30% of women and 17% of men experience major depressive disorder episodes over the course of their lives.
Examining the impact of eight types of early life stress on the onset of youth-onset depression, researchers found some had little impact on the development of the psychological disorder. Emotional abuse was more strongly associated with the development of major depressive disorder than other early stressors, such as poverty.
Comparing data from multiple neuroimaging studies, researchers found shared brain structural abnormalities between four psychiatric disorders, including schizophrenia and bipolar disorder. They also identified brain signatures unique to each condition.
Study reveals how the brain's opioid system is linked to mood changes associated with depression and anxiety. Neuroimaging revealed, in those with depression, there is a decreased number of opioid receptors in specific areas of the brain.