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lysosomes

Featured Genetics Neurology Neuroscience

·February 16, 2026·9 min read

Two Genetic “Hits” Required to Trigger Parkinson’s Neurodegeneration

Researchers find that a mutation in GBA1 must be paired with an ATP13A2 mutation to drive the neurodegeneration seen in Parkinson’s disease.

Featured Neurology Neuroscience

·December 11, 2022·3 min read

Swelling Along Brain’s Axons May Be True Culprit in Alzheimer’s Disease

The formation of plaques can cause the accumulation of spheroid-shaped swellings along axons near the amyloid plaque deposits. The swellings are caused by lysosomes, which digest cellular waste. As the swelling enlarges, it can block the transmission of signals from one area of the brain to another.

Featured Neurology Neuroscience

·June 2, 2022·5 min read

Evidence Mounts for Alternate Origins of Alzheimer’s Disease Plaques

A new mouse study reveals a breakdown in the process that clears brain cells of waste products precedes the buildup of amyloid plaques associated with Alzheimer's disease.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·May 3, 2019·4 min read

New method developed to target cause of Parkinson’s

Clioquinol, an anti-parasitic medication, overcomes the effect of mutations in the LRRK2 gene associated with Parkinson's disease by restoring the acidity of lysosomes and clearing out protein aggregates.

Featured Neurology

·September 8, 2017·4 min read

Interrupting Parkinson’s Disease

A new study reports antioxidant intervention during early stages of Parkinson's disease may help slow its progression.

Featured Neuroscience

·August 15, 2017·5 min read

Granulins Are Brain Treasure, Not Trash

A new tool allows researchers to observe granulins inside cells.

Featured Genetics Neuroscience

·August 7, 2017·3 min read

A New View for Protein Turnover in the Brain

Researchers discover lysosomes can travel to dendrites and also be recruited by dendritic spines.

Featured Genetics

·April 3, 2017·3 min read

Reversal of Aging Now Possible

Summary: A new study reports researchers have identified a substance that can help to induce the reversal of aging. Source:...

Image shows synuclein fibrils in neurons.

Featured Neurology

·August 22, 2016·3 min read

Tunneling Nanotubes Between Neurons Enable the Spread of Parkinson’s

Researchers have demonstrated the role of lysosomal vesicles in transporting α-synuclein aggregates.

Featured Genetics Neurology

·June 28, 2016·4 min read

Possible New Therapy for a Rare Childhood Disease

A new study reports bone marrow transplants can significantly delay the onset of motor deficits in mouse models of MLIV.

Image shows protein aggregation in the PPI treated cells.

Featured Neurology Neuroscience Videos

·May 10, 2016·3 min read

Accelerated Risk of Vascular Aging Linked to Chronic Use of Some Antacids

Researchers report the chronic use of drugs to treat heartburn and GERDS can increase the risk of cardiovascular disease, vascular dementia and renal failure.