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          leptin

          This shows a brain and food.
          FeaturedNeuroscience
          ·May 30, 2025·3 min read

          Tiny Brain Cell Cluster Found to Drive Obesity and Overeating

          Scientists have identified a small, specialized group of neurons in the mouse brain that directly influence eating behavior and weight gain. These PNOC/NPY cells, found in the hypothalamus, increase food intake when activated and are also present in the human brain.
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          This shows a brain and food.
          FeaturedGeneticsNeuroscience
          ·December 5, 2024·4 min read

          New Appetite Regulating Neurons Discovered

          Researchers have identified a previously unknown population of neurons in the hypothalamus that play a critical role in regulating appetite. These neurons express both leptin receptors and the BNC2 gene, making them highly responsive to hunger-suppressing signals and food-related sensory cues.
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          This shows a brain.
          FeaturedNeuroscience
          ·October 23, 2024·9 min read

          Neural Circuit Found to Regulate Chewing and Appetite

          New research has uncovered a simple neural circuit that connects hunger signals to jaw movements required for eating. Scientists identified a three-neuron pathway involving the hormone leptin and BDNF neurons, which controls the jaw's motor function.
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          This shows a woman under a UV light.
          FeaturedNeuroscience
          ·May 22, 2024·5 min read

          UV Light Increases Appetite But Suppresses Weight Gain

          A new study reveals that UV exposure can increase appetite while simultaneously preventing weight gain. This unexpected finding is attributed to UV's influence on hormones and neurotransmitters, leading to increased energy expenditure and the browning of subcutaneous fat. These insights could pave the way for innovative approaches to combat obesity and metabolic disorders.
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          This is a graphical abstract from the study
          FeaturedNeuroscience
          ·February 23, 2023·5 min read

          Leptin Helps Hungry Mice Choose Sex Over Food

          When their brains are stimulated with leptin, an appetite-suppressing hormone, hungry mice prioritize mating and interacting with mice of the opposite gender over eating.
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          This shows a crying child
          FeaturedNeurosciencePsychology
          ·December 12, 2022·5 min read

          A Possible Neural Link Between Early Life Trauma and Binge-Eating Disorder Discovered

          8 in 10 sufferers of binge eating disorders experienced trauma during childhood. Researchers discovered leptin is less effective in the lateral hypothalamus of those who suffered childhood trauma.
          Read More
          This shows a brain
          FeaturedNeuroscience
          ·October 24, 2021·2 min read

          How the Brain and Fat Tissue Communicate

          A new study aims to generate a model of how the brain and body fat communication system controls the production and release of leptin. The study aims to discover how metabolism is regulated under different environmental challenges.
          Read More
          This is a diagram from the study
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·April 6, 2021·4 min read

          Leptin Puts the Brakes on Eating via Novel Neurocircuit

          Researchers have identified novel neurocircuitry between midbrain structures which are modulated by leptin to control eating behaviors in mice.
          Read More
          This shows a rat
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·August 12, 2020·3 min read

          Exercise Makes Female Rats Hungrier and Sustains Weight Gain

          Study in rats reveals sex differences may play a key role in the effectiveness of exercise as an appetite regulator. Exercising female rats ate more than those who did not partake in physical activity. The same effect was not seen in males.
          Read More
          This shows the bushy fat neurons
          FeaturedNeuroscience
          ·July 22, 2020·5 min read

          How Neurons Reshape Inside Body Fat to Boost Its Calorie-Burning Capacity

          Normally bushy networks of neural fibers within fat tissue shrink in the absence of leptin, but grow back when the hormone is administered in drug form. The alterations influence the ability to burn energy stored in fat in mouse models.
          Read More
          This shows a pregnant woman making a heart shape with her hands over her belly
          FeaturedNeuroscience
          ·May 25, 2019·2 min read

          Don’t overdo omega-6 fat consumption during pregnancy

          Consuming too much omega 6 during pregnancy has been linked to an increased risk of neurodevelopmental issues in babies and pregnancy complications. In mice who had higher levels of linoleic acid in their diets, researchers noted altered concentrations of inflammatory proteins and a decrease in hormones that regulate fetal growth and development. Researchers stress the effects of a high linoleic acid concentration in diet are the same for both animal models and humans.
          Read More
          This shows a weighing scale, a tape measure and an apple
          FeaturedNeuroscienceOpen Neuroscience Articles
          ·May 2, 2019·3 min read

          New brain mechanisms regulating body weight identified: Rodent study

          Interleukin-6 interacts with leptin in the lateral parabrachial nucleus to reduce food intake. Reducing IL-6 in the IPBL increases weight gain and could help explain why some are more prone to overeating and obesity.
          Read More
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          This shows a man and woman's heads.

          Hormones Shape Love and Lust Differently in Male & Female Brains

          This shows a man wearing glasses.

          Cancer Drug Shows Promise In Treating AMD Vision Loss

          This shows a man, a brain, and blood vials.

          Middle-Age Clues: Blood Biomarkers Signal Alzheimer’s Risk Early

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          Friendship Synchronizes Brains

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