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leptin

This shows a weighing scale, a tape measure and an apple

Featured Neuroscience Open Neuroscience Articles

·May 2, 2019·3 min read

New brain mechanisms regulating body weight identified: Rodent study

Interleukin-6 interacts with leptin in the lateral parabrachial nucleus to reduce food intake. Reducing IL-6 in the IPBL increases weight gain and could help explain why some are more prone to overeating and obesity.

Featured Neuroscience Open Neuroscience Articles

·August 12, 2020·3 min read

Exercise Makes Female Rats Hungrier and Sustains Weight Gain

Study in rats reveals sex differences may play a key role in the effectiveness of exercise as an appetite regulator. Exercising female rats ate more than those who did not partake in physical activity. The same effect was not seen in males.

Featured Genetics Neuroscience

·April 19, 2018·4 min read

Neurons Derived From Super-Obese People Respond Differently to Appetite Hormone

According to researchers, neurons generated from super obese people are more likely to dysregulate hormones related to hunger and feeding behaviors.

The image shows the differences between normal bones and those of people with osteoporosis.

Featured Genetics

·June 13, 2014·3 min read

Proteins Causing Daytime Sleepiness Tied to Bone Formation

Researchers discover Orexin, a protein associated with daytime sleepiness, may also play a critical role in bone development.

This is a graphical abstract from the study

Featured Neuroscience

·February 23, 2023·5 min read

Leptin Helps Hungry Mice Choose Sex Over Food

When their brains are stimulated with leptin, an appetite-suppressing hormone, hungry mice prioritize mating and interacting with mice of the opposite gender over eating.

Featured Genetics Neuroscience

·November 19, 2018·3 min read

Is the Gut or Brain More Important in Regulating Appetite and Metabolism?

Researchers debate the roles of the gut and brain hormones play in regulating appetite and metabolism.

Featured Neuroscience Open Neuroscience Articles

·April 6, 2021·4 min read

Leptin Puts the Brakes on Eating via Novel Neurocircuit

Researchers have identified novel neurocircuitry between midbrain structures which are modulated by leptin to control eating behaviors in mice.

Featured Psychology

·May 16, 2016·3 min read

How Obese and Anorexic People React Differently to Taste

According to researchers, women who are obese and those suffering from anorexia respond differently to taste than those without an eating disorder.

Featured Neuroscience

·October 24, 2021·2 min read

How the Brain and Fat Tissue Communicate

A new study aims to generate a model of how the brain and body fat communication system controls the production and release of leptin. The study aims to discover how metabolism is regulated under different environmental challenges.

Featured Neuroscience

·July 22, 2020·5 min read

How Neurons Reshape Inside Body Fat to Boost Its Calorie-Burning Capacity

Normally bushy networks of neural fibers within fat tissue shrink in the absence of leptin, but grow back when the hormone is administered in drug form. The alterations influence the ability to burn energy stored in fat in mouse models.

Featured Genetics Neuroscience

·August 25, 2018·5 min read

Destructive Mechanism That Blocks the Brain from Knowing When to Stop Eating Identified

Researchers report mice fed a high fat diet produce an enzyme called MMP-2, which results in leptin being blocked from binding to its receptors. This, they report, prevents neurons from signaling that the stomach is full. The study suggests blocking MMP-2 may help people with obesity to lose weight.