Study supports effectiveness of new fast-acting antidepressant, esketamine nasal spray
Esketamine combined with antidepressants acts rapidly to help alleviate symptoms in those with treatment-resistant depression.... Read More...
ketamine
Ketamine: The illicit party psychedelic that promises to heal depression
Ketamine, an anesthetics which has been commonly used as an illicit party drug, is helping people overcome depression. The drug works rapidly and provides lasting relief from depressive symptoms for weeks after exposure. Researchers are examining how ketamine works in the brain to help positively influence behavior in those with mood disorders.... Read More...
Traces of Ketamine, Cocaine, Pharmaceuticals and Pesticides Found in Freshwater Shrimp
Researchers have found a diverse array of illicit drugs, including cocaine and ketamine, along with pesticides and pharmaceutical chemicals in British freshwater shrimp. While the concentrations of chemicals were considered low, researchers state there is a concern for the potential environmental risk this may pose to wildlife.... Read More...
New drug mimics benefits of ketamine for depression
NV-5138, a small molecule drug that mimics the action of ketamine, provides fast-acting antidepressant responses in rodent models of depression. The drug is currently undergoing Phase 1 testing in humans.... Read More...
Ketamine reverses neural changes underlying depression-related behaviors: Mouse study
The formation of prefrontal cortex dendritic spine formation sustains the remission of depressive related symptoms and behaviors following ketamine treatment by restoring lost spines. ... Read More...
Researchers Discover How a Critical Receptor is Involved in the Response to Fast-Acting Antidepressants Like Ketamine
The mGlu2 receptor plays a critical role in the effectiveness of ketamine for treating depression. ... Read More...
Ketamine and Naltrexone Combo Shows Promise for Depression and Addiction Treatments
A new study reveals the combination of ketamine with naltrexone can help treat symptoms of both depression and addiction.... Read More...
Are Near Death Experiences Hallucinations?
Researchers consider the neurobiology of near death experiences.... Read More...
New Insights Into Loss of Pleasure in Depression
A new study reveals a brain region that contributes to anhedonia, the loss of pleasure, in those with depression. The study also shows how ketamine acts on this brain region, explaining why the drug appears to be so effective at treating anhedonia.... Read More...
Ketamine’s Antidepressant Effects Tied to Opioid System in the Brain
Researchers report ketamine's antidepressive effects require activation of opioid receptors in the brain. The study highlights the interaction between depression, pain and opioid addiction. ... Read More...
Ketamine Acts Fast to Treat Depression and Its Effects Last, But How?
Researchers explore the mechanisms behind ketamine's effectiveness at treating depression. The study reports the long lasting effects of ketamine may be due to G proteins timing in moving back to lipid rafts.... Read More...
Ketamine and Psychedelic Drugs Change Structure of Neurons
A new study reveals psychedelics increase dendrites, dendritic spines and synapses, while ketamine may promote neuroplasticity. The findings could help develop new treatments for anxiety, depression and other related disorders.... Read More...