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Johns Hopkins Medicine

This shows someone erasing a drawing of a brain

Featured Neurology Neuroscience Open Neuroscience Articles

·May 14, 2019·4 min read

Brain changes linked with Alzheimer’s up to 30 years before symptoms appear

Researchers have identified average levels of biological and anatomical brain changes associated with Alzheimer's disease over thirty years before symptoms appear. In those with genetic risk factors for Alzheimer's, researchers found changes in cognitive performance up to 15 years before becoming symptomatic. Changes in Tau levels in the cerebral spinal fluid appeared up to 34 years before dementia symptoms occurred, and physical changes to the medial temporal lobe were apparent up to 9 years before cognitive impairment was apparent.

This shows the researcher's daughter and the broccoli sprouts she is growing

Featured Neuroscience Open Neuroscience Articles Psychology

·May 8, 2019·10 min read

Broccoli sprout compound may restore brain chemistry imbalance linked to schizophrenia

Sulforaphane, a compound derived from broccoli sprouts, may be a useful new treatment for those suffering from schizophrenia. In a recent set of animal and human studies, researchers characterized novel chemical imbalances in the brain related to glutamate. Levels of glutamate, they discovered, can be altered by administering sulforaphane.

Featured Genetics Neurology Neuroscience

·May 1, 2019·5 min read

Restoring brain function in mice with symptoms of Alzheimer’s disease

Senolytic drugs administered to mice reduced senescent cells around amyloid plaques by more than 90% and decreased neuroinflammation by 50%. Mice treated with the drug combination also showed improvements in spatial memory, compared to other Alzheimer's model mice who received no treatment. The findings could have positive implications for the treatment of Alzheimer's disease in people with the condition.

Featured Neuroscience Psychology

·April 23, 2019·5 min read

Study suggests overdiagnosis of schizophrenia

Researchers provide evidence schizophrenia may be overdiangosed in patients experiencing anxiety and other mood disorders.

This shows a brain overlayed on a person's head with a swirly, psychedelic background

Featured Neuroscience Psychology

·April 4, 2019·5 min read

Psychedelic drug MDMA may reawaken ‘critical period’ in brain to help treat PTSD

MDMA, a psychedelic drug, has successfully been used to reopen the 'critical period' of learning the reward values of social behaviors. Researchers report, in mature mice given MDMA, oxytocin triggers signaling in synapses that help encode social learning and memory, a process that does not usually occur in older animals. The findings could help in the development of treatments for PTSD and other disorders.

this diagram shows how the drug combinations lead to apoptosis in brain cancer

Brain Cancer Featured Neurology Neuroscience

·March 22, 2019·4 min read

New drug combination shows promise for common pediatric brain tumor

Combining carboplatin, a common chemotherapy drug, with everolimus, a drug that blocks mTOR, is effective at inducing apoptosis and slowing tumor growth in patients with pediatric low-grade glioma brain cancer.

Featured Neurology Neuroscience Open Neuroscience Articles

·February 26, 2019·9 min read

Hip Fractures May Be An Early Sign of Alzheimer’s in Older People

Researchers report they have identified biomarkers of Alzheimer's disease in spinal fluid samples of a significant number of older patients hospitalized as a result of hip fractures. The study suggests neural alterations that lead to poor balance in older people may signify an increased risk of falls that result in hip fractures, and Alzheimer's disease. Researchers suggest the hip fracture, therefore, may serve as an early sign of Alzheimer's in older patients.

Featured Neurology Neuroscience Neuroscience Videos Open Neuroscience Articles

·February 5, 2019·6 min read

New Scan Technique Reveals Neuroinflammation Associated with Post-Treatment Lyme Disease Syndrome

A new neuroimaging study reveals 12 people with documented post-treatment Lyme disease syndrome have an elevation of a chemical marker associated with neuroinflammation. The findings could help develop new treatments for the pain, fatigue and brain fog associated with PTLDS.

Featured Genetics Neurology Psychology

·January 16, 2019·5 min read

Differences Among Neurons that Coincide with Psychiatric Conditions

A new study reveals differences in genes in four areas of the brain that contribute to psychiatric disorders.

Featured Genetics Neuroscience

·December 17, 2018·7 min read

How Marijuana May Damage the Teen Brain: Mouse Study

A new study reveals how marijuana can impede brain development and contribute to increased risks of mental health problems in teens with the DISC1 gene.

Featured Genetics Neuroscience Open Neuroscience Articles

·September 20, 2018·5 min read

Octopuses Given Ecstasy Reveal Genetic Link to Evolution of Social Behaviors in Humans

Testing the behavioral reaction to MDMA in octopuses, researchers report they have discovered evidence of an evolutionary link between the sea creatures and humans.

Featured Psychology

·July 21, 2018·7 min read

Beef Jerky and Other Processed Meats Associated with Manic Episodes

A new study reports eating processed meats could contribute to mania associated with bipolar disorder. Researchers found people who had been hospitalized for mania were 3.5 times more likely to have eaten cured meats prior to admittance.