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ion channels

·March 18, 2020·4 min read

Ball-and-chain inactivation of ion channels visualized by cryo-electron microscopy

Ion channels use a "ball-and-chain" mechanism to help regulate ion flow. Findings confirm a long-standing hypothesis about ion channels and provide key advances in understanding the basic biological processes at work.

Featured Neuroscience

·August 11, 2018·5 min read

An Ion Channel Differentiates Newborn and Mature Neurons in the Adult Brain

Researchers report newborn granule cells in the dentate gyrus become less excitable after three weeks. The loss of excitability is crucial for the functioning of mature neurons.

Featured Neurology

·February 26, 2018·4 min read

New Way to Stop Inflammation in Alzheimer’s and Immune System Disorders

Researchers report new findings about the immune system could help treat inflammation in Alzheimer's disease and could save people from deadly inflammation associated with sepsis.

Image shows the 3D structure of the glutamate receptor.

Featured Neuroscience

·July 24, 2017·4 min read

First Image of Major Brain Receptor in Action Captured

Using cryo-electron microscopy, researchers have been able to capture how glutamate opens glutamate receptor ion channels. The Nature study provides significant insight into how receptors can mediate brain function.

Featured Neurology Open Neuroscience Articles Pain

·October 11, 2016·4 min read

How the Naked Mole Rat Escapes Inflammatory Pain

Findings from a study of naked mole rats could be important for helping develop pain therapies for humans.

Featured Neuroscience

·October 5, 2015·4 min read

How Excited Neurons Settle Down

Researchers have detailed the structure of the Slo2.2 channel and offer new insights into how this channel works.

Featured Neuroscience Open Neuroscience Articles

·September 8, 2015·3 min read

Reversing Animal Behavior Through Synaptic Engineering

A new study reports animal behavior can be reversed by manipulating neural communication.

Featured Neuroscience

·July 20, 2015·3 min read

Neurons Learning to Remember: Mechanism of Neural Information Storage Identified

Researchers identify a calcium dependent mechanism for neuronal information storage.

The image shows an atomic force microscope recording needle illustration.

Electrophysiology Featured

·February 17, 2015·3 min read

Voltage Tester for Beating Cardiac Cells

Researchers have successfully recorded current in membrane channels of contracting cardiac cells using the patch clamp technique and an atomic force microscope.