Type 1 diabetes may have an impact on the developing brain in children
Children with type 1 diabetes have slower growth of total cortical and subcortical gray and white matter compared to their peers without diabetes. ... Read More...
insulin
Research sheds new light on how brain stem cells are activated
A new study in fruit fly models reveals STRIPAK components act as a switch to turn off quiescence and turn on the reactivation of neural stem cells.... Read More...
Gene mutation evolved to cope with modern high-sugar diets
A variant of the CHC22 gene evolved to help people adapt to the modern, higher sugar diet. However, many people still retain the older version of the genetic variant, which does not allow for correct metabolism of modern diets and may be linked to an increased risk of developing diabetes.... Read More...
Does insulin resistance cause fibromyalgia?
Study finds a pathogenic relationship between insulin resistance and fibromyalgia. Treating fibromyalgia with metformin, a drug that combats insulin resistance, resulted in a dramatic reduction of pain levels for patients.... Read More...
Comfort food leads to more weight gain during stress
A combination of chronic stress and high-calorie diets raised insulin levels tenfold in the amygdala of mice. Prolonged high levels of insulin in the central amygdala resulted in neurons becoming desensitized to insulin. The desensitized neurons boosted NPY levels, which promoted eating and reduced the normal homeostasis response to burn calories. The findings may shed light on why some indulge in high-calorie foods when stressed, and why this may lead to obesity.... Read More...
New insight into how obesity and insulin resistance can impair cognition
Adora2a mediating signaling in vascular endothelial cells disrupts the blood-brain barrier in obesity. This, researchers report, could be an underlying mechanism for synaptic plasticity and cognitive deficits in those with insulin resistance and obesity.... Read More...
Researchers discover crucial link between brain and gut stem cells
The insulin-like growth factor II gene plays a critical role in adult stem cell maintenance of both the intestine and the brain. Findings suggest IGF-2 is essential for multiple stem cell types, including those implicated in cognitive function and renewing the lining of the small intestine.... Read More...
Insulin Signaling Failures in the Brain Linked to Alzheimer’s Disease
Insulin signaling plays a role in regulating synaptic function, glucose homeostasis, and cognition, a new study reports. Impairments in insulin signaling result in metabolic defects, in addition to memory and learning deficits, mirroring the cognitive impairments associated with Alzheimer's disease.... Read More...
Insulin Signaling Failures in Brain Linked to Alzheimer’s
A new study reveals impaired insulin signaling in the brain negatively affects cognition, memory and learning. The findings shed light on why those with type 2 diabetes are at greater risk of developing Alzheimer's disease.... Read More...
Sugar’s Sick Secrets: How Industry Forces Have Manipulated Science to Downplay the Harm
UCSF researchers report the food and beverage industries push sugary products while obfuscating the significant health issues added sugars can cause. The findings shed light on sugars' link to disease and exposes industrial tactics to downplay the public health risks of diets too high in sugar.... Read More...
Is the Gut or Brain More Important in Regulating Appetite and Metabolism?
Researchers debate the roles of the gut and brain hormones play in regulating appetite and metabolism.... Read More...
Can’t Exercise? Taking a Hot Bath Improves Inflammation and Metabolism
For those who find it difficult to exercise, taking a hot bath can help improve inflammation and glucose levels, a new study reports.... Read More...