Insulin binding receptors are predominantly located in the microvessels within the blood-brain barrier. In patients with Alzheimer's, the abundance of these receptors is decreased. This decrease could lead to the loss of insulin response in the Alzheimer's brain.
Study found childhood poverty was associated with insulin resistance in adults in their late 20s. Immune cell aging was a mechanism through which poverty was linked to insulin resistance.
Summary: In males, a genetic variant of DUSP8 can increase the risk of type 2 diabetes by impairing the brain’s...
Study finds a pathogenic relationship between insulin resistance and fibromyalgia. Treating fibromyalgia with metformin, a drug that combats insulin resistance, resulted in a dramatic reduction of pain levels for patients.
Adora2a mediating signaling in vascular endothelial cells disrupts the blood-brain barrier in obesity. This, researchers report, could be an underlying mechanism for synaptic plasticity and cognitive deficits in those with insulin resistance and obesity.
According to researchers, people with diabetes may be at increased risk of suffering from depression as a result of biological problems in regulating sugar levels that influence emotional response in the brain. Using EEG, researchers discovered those with higher levels of insulin resistance showed greater response to negative images.
A new study reports insulin resistance is linked to accelerated cognitive decline.
A new study reports people with insulin resistance, a feature common in type 2 diabetes, can increase the risk for developing Alzheimer's disease.