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insulin resistance

·May 31, 2024·3 min read

Ketones May Help Reverse Cognitive Decline

As we age, our brain naturally becomes more insulin resistant, disrupting neuron communication and leading to cognitive decline and neurodegeneration. Researchers studied how acute insulin resistance impacts neuronal function before symptoms of chronic conditions like Alzheimer's manifest.

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Featured Neurology Neuroscience

·November 7, 2023·4 min read

High-Sugar Diets May Fuel Brain Decline

Research suggests a high-sugar diet, commonly associated with obesity, leads to insulin resistance in the brain and may heighten the risk of neurodegenerative diseases like Alzheimer's. The study reveals that this insulin resistance impairs glial cells' ability to clear neuronal debris, a crucial process for preventing neurodegeneration.

Featured Neurology Neuroscience

·December 17, 2022·5 min read

Why Does the Alzheimer’s Brain Become Insulin-Resistant?

Insulin binding receptors are predominantly located in the microvessels within the blood-brain barrier. In patients with Alzheimer's, the abundance of these receptors is decreased. This decrease could lead to the loss of insulin response in the Alzheimer's brain.

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Featured Neuroscience Psychology

·July 25, 2022·5 min read

Study Links Insulin Resistance and Advanced Cell Aging With Childhood Poverty

Study found childhood poverty was associated with insulin resistance in adults in their late 20s. Immune cell aging was a mechanism through which poverty was linked to insulin resistance.

Featured Genetics Neurology

·August 21, 2020·4 min read

A Gatekeeper Against Insulin Resistance in the Brain

Summary: In males, a genetic variant of DUSP8 can increase the risk of type 2 diabetes by impairing the brain’s...

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Featured Neurology Neuroscience Open Neuroscience Articles Pain

·May 7, 2019·4 min read

Does insulin resistance cause fibromyalgia?

Study finds a pathogenic relationship between insulin resistance and fibromyalgia. Treating fibromyalgia with metformin, a drug that combats insulin resistance, resulted in a dramatic reduction of pain levels for patients.

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·April 22, 2019·8 min read

New insight into how obesity and insulin resistance can impair cognition

Adora2a mediating signaling in vascular endothelial cells disrupts the blood-brain barrier in obesity. This, researchers report, could be an underlying mechanism for synaptic plasticity and cognitive deficits in those with insulin resistance and obesity.

Featured Neuroscience Psychology

·May 7, 2018·5 min read

Brain Activity May Explain Diabetics’ Negative Feelings and Increased Depression Risk

According to researchers, people with diabetes may be at increased risk of suffering from depression as a result of biological problems in regulating sugar levels that influence emotional response in the brain. Using EEG, researchers discovered those with higher levels of insulin resistance showed greater response to negative images.