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immune system

This diagram shows how lupus affects the body

·July 2, 2019·3 min read

B cells off the rails early in lupus

A key finding in the origins of lupus has been discovered. In those with systemic lupus erythematosus, B cells are abnormally activated. This results in the production of antibodies which react against the patient's own tissue, causing a range of symptoms including rashes, joint pain, and fatigue.

Featured Neurology Neuroscience Open Neuroscience Articles

·June 29, 2019·4 min read

Newly discovered immune cells at the frontline of HIV infection

A newly discovered subset of dendritic cells have been implicated in sexually transmitted HIV infection. The CD11c+ dendritic cells are found in human genital tissue at the epithelial level. They are the first immune cells to interact with the HIV virus. The cells directly transfer the virus to CD4 T cells, making them key drivers in HIV transmission.

Featured Neurology Neuroscience

·June 26, 2019·4 min read

Is multiple sclerosis linked to childhood viral infections?

Exposure to viral infections in the brain during childhood has been linked to an increased risk of developing multiple sclerosis later in life.

Featured Neurology Neuroscience

·June 25, 2019·2 min read

Smokers may have impaired neuroimmune function

Smokers may have reduced neuroimmune function compared to their non-smoking peers. Researchers report restoring the immune system may benefit smokers. Immune dysfunction is linked to cognitive dysfunction.

Featured Genetics Neurology Neuroscience

·June 18, 2019·3 min read

How common gut bacteria trigger a lethal autoimmune disease

A common gut bacterium can trigger antiphospholipid syndrome, an autoimmune disease that affects young women, in those with a genetic predisposition.

This is a drawing of a fetus attached to a placenta

Featured Neuroscience

·June 18, 2019·5 min read

New evidence supports the presence of microbes in the placenta

Microbes found in the placenta may play a key role in shaping the developing fetal immune system.

This shows how C3 microglia acts to resolve RP

Featured Neurology Neuroscience Visual Neuroscience

·June 17, 2019·4 min read

Immune system can slow degenerative eye disease: Mouse study

Study reveals C3, which can cause damage in some eye diseases, may help to slow the progression of retinitis pigmentosa.

This is a super cute newborn baby smiling

Featured Neurology Neuroscience

·June 13, 2019·4 min read

How is a mother’s immunity transferred to her baby?

Study reveals how a pregnant woman's vaccine-induced immunities are transferred to her offspring via the placenta. The findings have positive implications for the development of new, more effective maternal vaccines.

This shows bacteria and a pregnant woman

Featured Neurology Neuroscience

·June 12, 2019·4 min read

Women caught in a pickle by their own immune systems

Pregnancy Compensation Hypothesis may explain why women are more prone to developing autoimmune diseases, like multiple sclerosis and lupus, than men.

Featured Genetics Neuroscience Open Neuroscience Articles

·June 11, 2019·4 min read

Genetics influence how protective childhood vaccines are for individual infants

A large, genome-wide study in children reveals genetic variants associated with differing levels of antibodies produced as a result of three common childhood vaccinations. Researchers identified two genetic loci associated with the persistence of vaccine-induced immunity following early life vaccinations. The results may help clinicians tailor personalized vaccine schedules to maximize the effectiveness of immunizations.

Featured Neurology Neuroscience Pain

·June 11, 2019·3 min read

Promising treatment option for Complex Regional Pain Syndrome

Blocking the activity of interleukin-1 in mouse models of complex regional pain syndrome (CRPS) helped reverse symptoms. Researchers say patients with CRPS should respond to immune-based treatments which reduce some of the disease features.

This shows a virus like protein structure

Featured Neurology Neuroscience Open Neuroscience Articles

·June 11, 2019·4 min read

Memory Preserver: Researchers Develop Vaccine That Could Protect Against Alzheimer’s

Researchers have engineered a vaccine using virus-like particles that target Tau tangles in mouse models of Alzheimer's disease. Following the administration of the vaccine, the mice developed antibodies that cleared tau proteins, with the response lasting for a month. The mice also showed improvements in memory based tests and had less brain shrinkage than their peers who did not receive the vaccine. This suggests the vaccine prevented apoptosis. Researchers hope to move the vaccine to human clinical trials in the future.

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immune system

B cells off the rails early in lupus

Newly discovered immune cells at the frontline of HIV infection

Is multiple sclerosis linked to childhood viral infections?

Smokers may have impaired neuroimmune function

How common gut bacteria trigger a lethal autoimmune disease

New evidence supports the presence of microbes in the placenta

Immune system can slow degenerative eye disease: Mouse study

How is a mother’s immunity transferred to her baby?

Women caught in a pickle by their own immune systems

Genetics influence how protective childhood vaccines are for individual infants

Promising treatment option for Complex Regional Pain Syndrome

Memory Preserver: Researchers Develop Vaccine That Could Protect Against Alzheimer’s

How Your Brain Saves Nostalgia From Scandals

Dietary Lecithin Linked to Lower Cognitive Impairment

How to Map Brain Circuits Without Touching a Single Neuron

Overlooked Blood Cell May Tracks Parkinson’s Brain Changes

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