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immune system

·October 3, 2019·5 min read

Parkinson’s disease is also present in the blood

Parkinson's disease involves monocytic alterations in the blood. The cells have reduced viability and are unresponsive to specific stimuli, which could have relevant consequences for the progression of Parkinson's. Immune modulation medications may be a new treatment option to inhibit neurodegeneration associated with PD.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·October 1, 2019·3 min read

A brain protein that could put the brakes on Alzheimer’s

Reducing the expression of the protein TOM1 in mouse models of Alzheimer's disease increased the pathology, exacerbated cognitive problems, and raised levels of inflammation in the brain. Restoring TOM1 reversed the effects. Findings suggest a new therapeutic target for treating dementia.

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Brain Cancer Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·September 27, 2019·3 min read

Study finds age hinders cancer development

Alterations associated with aging and cellular senescence may be linked to a decrease in cell proliferation, while cancer shifts towards increased cell division. The study challenges the traditional view that cancer risks increase as we age, finding the aging process may suppress the development of cancer.

Featured Neurology Neuroscience Open Neuroscience Articles Psychology

·September 19, 2019·4 min read

Autoantibodies in pregnancy: A cause of behavioral disorders in the child?

Embryonic damage caused by autoantibodies is implicated in a range of behavioral and psychological disorders, including schizophrenia, autism, and ADHD.

Featured Neurology Neuroscience

·September 18, 2019·5 min read

How sleepless nights compromise the health of your gut

Study reveals the function of specific immune cells, well documented as playing a significant role in gut health, is directly controlled by our circadian clock.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·September 16, 2019·5 min read

Transplanted brain stem cells survive without anti-rejection drugs

Researchers have developed a new method to transplant neural stem cells into mice without the need for lifelong anti-rejection medications.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·September 16, 2019·5 min read

A new approach for treating inflammation

Targeting the miR-199, a microRNA which reduces the migration of neutrophils could potentially reduce inflammation without compromising the immune system.

Brain Cancer Featured Genetics Neurology Neuroscience

·September 16, 2019·4 min read

How lymphoma cells metastasize to the brain

In aging mice, chronic inflammatory processes lead lymphoma cells which entered the brain to be retained, rather than released directly back into the blood.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·September 16, 2019·4 min read

Alzheimer’s disease risk gene APOE4 impairs function of brain immune cells

APOE4 increases the inflammatory response of human microglia while reducing cellular migration. The gene also impairs the metabolic activity of the immune cells. The findings show APOE4 has a profound impact on the basic functions of microglia.

Featured Neurology Neuroscience Open Neuroscience Articles

·September 5, 2019·5 min read

Hookworm infection may cause cognitive impairment earlier than thought

Human hookworm infection, even at low levels, can cause rapid, acute and measurable cognitive impairments. Using rodent models, researchers found a link between the parasitic infection and alterations in both the microbiome and cognitive development.

Featured Genetics Neurology Neuroscience

·August 30, 2019·4 min read

Creation of new brain cells plays an underappreciated role in Alzheimer’s disease

Microglia may play a significant role in disrupting neurogenesis in those with Alzheimer's disease. When mice were given drugs which caused microglial cells to die, neurogenesis returned to normal.

Featured Neurology Neuroscience Open Neuroscience Articles

·August 26, 2019·7 min read

An innovative new diagnostic for Lyme disease

Researchers have discovered six candidate biomarkers for Lyme disease. A newly developed test can help identify the disease which, until now, has been notoriously difficult to detect.