FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology·February 24, 2020·4 min readAntibodies: The body’s own antidepressantsWhen autoantibodies are able to enter the bran and act on NMDA receptors, people experience relief from symptoms of anxiety, depression, and stress.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·February 11, 2020·6 min readHuman gut-in-a-dish model helps define ‘leaky gut,’ and outline a pathway to treatmentA new 3D human gut organoid reveals the molecular system that keeps the intestinal linings sealed and how dysfunction can occur. Findings reveal the diabetes drug metformin can help strengthen the intestinal lining.Read More
FeaturedNeuroscienceOpen Neuroscience Articles·February 11, 2020·4 min readHow the brain’s immune system could be harnessed to improve memoryAltering microglia in rats helped enhance their performance in memory tasks by up to 50%. The findings could help to develop new therapies that enhance memory function and prevent cognitive decline in humans.Read More
FeaturedNeuroscience·February 7, 2020·3 min readBrain cells long thought of as passive play key role in memoryMicroglia, key immune cells in the brain, may play a significant role in memory retention.Read More
FeaturedNeurologyNeuroscience·February 5, 2020·3 min readActivating immune cells could revitalize the aging brainActivating group 2 innate lymphoid cells in aging brains helps improve memory in mice. The findings could help in the development of treatments for neurodegenerative diseases associated with aging.Read More
FeaturedGeneticsNeurologyNeuroscience·February 5, 2020·3 min readParkinson’s and the immune systemResearchers provide new evidence of the link between Parkinson's disease and the immune system.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience Articles·February 4, 2020·5 min readDopamine signals may guide migration of immune cells to infection sitesDopamine may play a role in activating immune cells to migrate in the early stages of infection.Read More
FeaturedNeurologyNeuroscienceOpen Neuroscience Articles·January 30, 2020·3 min readImmune response in brain and spinal cord could offer clues to treating neurological diseasesMicroglia can interfere with macrophages, preventing the movement of these blood immune cells to injury sites. The findings could help in the development of new treatments for multiple sclerosis, Alzheimer's disease, and spinal cord injury.Read More
Brain CancerFeaturedGeneticsNeurologyNeuroscience·January 15, 2020·3 min readScientists breach brain barriers to attack tumorsIntroducing VEGF-C into the cerebrospinal fluid of mouse models of glioblastoma, researchers noted increased levels of T cell response to the cancerous tumors. When combined with immune system checkpoint inhibitors, the VEGF-C treatment significantly extended the life span of the mice with glioblastoma brain cancer.Read More
FeaturedGeneticsNeuroscienceOpen Neuroscience ArticlesPsychology·January 14, 2020·3 min readHyperactive immune system gene causes schizophrenia-like changesStudy implicates C4, an immune system gene, in schizophrenia pathogenesis.Read More
FeaturedNeuroscienceOpen Neuroscience ArticlesPsychology·January 14, 2020·6 min readT. gondii cat parasite reduces general anxiety in infected mice, not just fear of feline predatorsMice infected with the Toxoplasma gondii parasite showed no selective reduction in fear of feline predators. Findings reveal chronic T. gondii infection reduces anxiety and risk-aversion while increasing curiosity and exploratory behaviors.Read More
FeaturedNeurologyNeuroscience·January 8, 2020·4 min readGut microbes may improve stroke recoveryMicrobiota-derived short-chain fatty acids (SCFA) modulate stroke recovery. The effect was mediated by circulating lymphocytes on microglia activation. The study reports SCFAs could be a potential therapeutic to improve post-stroke recovery.Read More