Both food timing and the integrity of the internal clock in the liver altered rhythms of metabolism in mice. Almost half of the rhythmic genes are regulated by both the internal clock and when food is ingested.
Normally bushy networks of neural fibers within fat tissue shrink in the absence of leptin, but grow back when the hormone is administered in drug form. The alterations influence the ability to burn energy stored in fat in mouse models.
Researchers discover an important function of gamma-secretase in cells that is critical for lipid homeostasis in the brain.
Study shows how circadian clock mechanisms boost our ability to maintain our bodies when we are most active.
Study reveals the function of specific immune cells, well documented as playing a significant role in gut health, is directly controlled by our circadian clock.
A new study shows how the microbiome communicates with cells producing serotonin to influence blood sugar levels. The microbiome can worsen metabolism by signaling to cells in the gut that produce serotonin. This drives up serotonin levels. The rise in blood serotonin levels causes metabolic problems.
Galanin expressing neurons are selectively active during rebound sleep. The expression of galanin increases after neuronal activity and sleep deprivation. The neuropeptide plays a critical role in sleep homeostasis.
High-fat diets are not only bad for your waistline, they are also bad for your brain health. A new study reveals high-fat diets contribute to hypothalamic inflammation which occurs long before symptoms of obesity arise.
Hippocampal neurons become longer and stronger following a period of sleep deprivation. The study supports the hypothesis that sleep may weaken synapses, which are strengthened from learning, allowing for learning to occur after waking.