Normally bushy networks of neural fibers within fat tissue shrink in the absence of leptin, but grow back when the hormone is administered in drug form. The alterations influence the ability to burn energy stored in fat in mouse models.
A metabolite produced by lactic acid bacteria binds to the third hydroxycarboxylic acid receptor (HCA), signalling the immune system. Researchers believe the receptor evolved to allow great apes to consume foods that were starting to decay. They suggest the receptor could mediate some beneficial and anti-inflammatory effects of lactic acid in humans, and could serve as a target to treat inflammatory diseases.
Galanin expressing neurons are selectively active during rebound sleep. The expression of galanin increases after neuronal activity and sleep deprivation. The neuropeptide plays a critical role in sleep homeostasis.
Study reveals how the body produces different health-promoting signaling molecules in an organ-specific manner following exercise at different points during the day.
A new study reports researchers have discovered a brain mechanism that could be a suitable target to prevent addiction and tolerance to opioids.
Researchers have identified a set of neurons, located in a region of the hypothalamus, that may be the switch that turns the brain off, allowing for sleep. The neurons are also tied to body temperature regulation.
Researchers have identified novel neural pathways that help regulate sleep and wakefulness.
Researchers report on how specific neurons can process sensory information about temperature and facilitate a change in behavior to adapt to the climate.