glioblastoma multiforme

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glioblastoma multiforme

This is a drawing of a brain in a castle

Brain Cancer Featured Genetics Neurology Neuroscience

·January 15, 2020·3 min read

Scientists breach brain barriers to attack tumors

Introducing VEGF-C into the cerebrospinal fluid of mouse models of glioblastoma, researchers noted increased levels of T cell response to the cancerous tumors. When combined with immune system checkpoint inhibitors, the VEGF-C treatment significantly extended the life span of the mice with glioblastoma brain cancer.

Brain Cancer Featured Genetics Neurology Neuroscience

·November 21, 2019·5 min read

Non-coding DNA located outside chromosomes may help drive glioblastoma

Extra DNA is critical for maintaining cancer-causing gene activation and supporting the cancer cell's ability to survive.

Brain Cancer Featured Neurology Neuroscience

·September 14, 2019·4 min read

Existing drug could treat aggressive brain cancer

Surfen, a compound molecule used for drug delivery of insulin could block tumor growth for patients with glioblastoma brain cancer.

Brain Cancer Featured Neurology Neuroscience

·August 27, 2019·4 min read

Researchers take aim at circadian clock in deadly brain cancer

Glioblastoma stem cells' circadian clocks ramp up the cells' metabolism, making them stronger, more resistant to treatment, and able to divide and multiply more rapidly. By targeting the stem cells with a small molecule drug, researchers found mice models lived longer and their tumors shrank.

Brain Cancer Featured Neurology Neuroscience Open Neuroscience Articles

·August 19, 2019·4 min read

Glioblastoma brain cancer could be diagnosed with simple blood test in future

Novel biomarkers for glioblastoma brain cancer have been identified in bodily fluids. The discovery may lead to a new, simple, non-invasive blood test to detect brain cancer in the future.

This shows brain slices with a glioblastoma tumor

Brain Cancer Featured Neurology Neuroscience

·August 8, 2019·5 min read

Adding MS drug to targeted cancer therapy may improve glioblastoma outcomes

Teriflunomide, a drug commonly used to treat multiple sclerosis, shows promise for the treatment of glioblastoma when coupled with targeted cancer therapies.

Brain Cancer Featured Genetics Neurology Neuroscience

·July 19, 2019·6 min read

Study hints at why an aggressive form of brain cancer is hard to treat

Genetics and microenvironment influence the frequency of glioblastoma cells. Researchers provide a new blueprint for glioblastoma, integrating the malignant cell programs, cancer cell plasticity, and modulation by genetic drivers. The findings shed light on why this form of cancer is so hard to treat effectively.

This shows macrophages in GBM tissue samples

Brain Cancer Featured Neurology Neuroscience

·June 25, 2019·4 min read

Scientists track brain tumor turncoats with advanced imaging

Advanced imaging techniques visualize macrophages in brain tumors in mouse models of glioblastoma.

Brain Cancer Featured Genetics Neurology Neuroscience

·June 10, 2019·5 min read

Study finds macrophages’ pathway to nurture PTEN-deficient glioblastoma: Mouse study

PTEN deficiency drives an increased expression of LOX. LOX attracts macrophages which protect gliobastoma brain cancer cells and provide growth factor support for the tumor, a new mouse study reveals.

Brain Cancer Featured Neurology Neuroscience Open Neuroscience Articles

·May 30, 2019·4 min read

Pairing of glutamine-targeting drug and ketogenic diet fights glioblastoma in mice

Combining an antibiotic drug that targets glutamine with the ketogenic diet helps kill glioblastoma cancer cells, reversing symptoms of the disease and improving survivability in mouse models.

This image shows a syringe and medical paper work

Brain Cancer Featured Neurology Neuroscience

·March 31, 2019·4 min read

New glioblastoma vaccine shows promising results in phase Ib clinical trial

A new vaccine for glioblastoma brain cancer suspends tumor growth and is well tolerated by patients, according to the results of an early phase clinical trial.

Brain Cancer Featured Genetics Neurology Neuroscience

·February 11, 2019·5 min read

Immunotherapy Can Be Effective in Treating People with Recurrent Glioblastoma

Researchers report administering immunotherapy treatment prior to surgery for those with recurring glioblastoma brain cancer is more effective that using the treatment after surgery.

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