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          genetic engineering

          This shows a brain.
          FeaturedGeneticsNeurologyNeuroscience
          ·May 21, 2025·5 min read

          AI-Guided Gene Vectors Precisely Target Brain and Spinal Cells

          Scientists have engineered dozens of adeno-associated virus (AAV) systems that ferry genes to specific neuron and glial subtypes in the brain and spinal cord with unprecedented accuracy. Powered by AI-selected DNA “light switches,” the vectors can switch on therapeutic or research genes only in targeted cells—eliminating the need for transgenic animals and enabling fine-grained circuit mapping, activation, or silencing.
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          This shows a brain.
          FeaturedGeneticsNeurologyNeuroscience
          ·August 5, 2024·5 min read

          Genetically Engineered Parasite Delivers Drugs to the Brain

          Researchers genetically engineered the parasite Toxoplasma gondii to deliver drugs across the blood-brain barrier. This innovative approach has been used to deliver therapeutic proteins to neurons, showing promise for treating neurological conditions like Rett syndrome. The research highlights the potential for parasites to act as delivery vehicles for large molecules that typically struggle to penetrate the brain. This breakthrough could lead to new treatments for a variety of neurological disorders.
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          This shows the outline of two heads
          FeaturedGeneticsNeurologyNeuroscience
          ·April 20, 2023·5 min read

          Engineered Cells Offer Promise for Treating ALS and Blinding Diseases

          Engineered stem cells may lead to personalized treatments for a range of neurological and visual disorders, a new study reports. Transplanting engineered induced pluripotent stem cells into the eyes of rodents with retinal degeneration led to the protection of cells in the eyes that support vision. In ALS models, transplanting cells into the spinal cord protected movement controlling cells. The engineered cells also created astrocytes and did not result in tumor formation.
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          This shows DNA
          FeaturedGeneticsNeurologyNeuroscience
          ·March 16, 2023·5 min read

          DNA Treatment Could Delay Paralysis That Strikes Nearly All Patients With ALS

          DNA designer therapeutics restored levels of a protein critical to motor neuron function, restoring the activity that is impaired as a result of ALS.
          Read More
          This shows heart shaped wind chimes
          FeaturedNeuroscience
          ·January 27, 2023·6 min read

          Fresh Questions About Oxytocin as the ‘Love Hormone’ Behind Pair Bonding

          The "love hormone" oxytocin may not play as critical a role in bonding as previously believed. Removing the oxytocin receptor in animal models still resulted in monogamous mating, attachment, and parental bonding behaviors, although females without the receptor produced milk in smaller quantities. Findings reveal parenting and bonding aren't purely dictated by oxytocin receptors.
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          This shows stem cells
          FeaturedGeneticsPsychology
          ·December 21, 2020·4 min read

          Gene Pathway Linked to Schizophrenia Identified Through Stem Cell Engineering

          Using human-induced pluripotent stem cells, researchers have identified a gene signaling pathway linked to a higher risk of developing schizophrenia.
          Read More
          striatum brain
          FeaturedNeurologyNeuroscience
          ·May 17, 2018·6 min read

          How the Brain Orchestrates Movement

          Researchers shed light on what happens to specific neurons when neurodegenerative diseases impact movement. The findings could help in the development of new treatments for Parkinson's and Huntington's disease.
          Read More
          Scientists created a mouse model of ALS and FTD caused by mutations in the C9ORF72 gene. Credit: Courtesy of Petrucelli lab, Mayo Clinic, Jacksonville, Fla.
          FeaturedGenetics
          ·May 22, 2015·4 min read

          Scientists Create Mice with a Major Genetic Cause of ALS and FTD

          Researchers believe mouse could provide a new platform for testing treatments for several neurodegenerative diseases.
          Read More
          The image shows some small orange dots hitting some blue bubbles.
          ElectrophysiologyFeaturedGenetics
          ·February 18, 2014·2 min read

          Molecular Biology Mystery Unravelled

          Researchers use new genetic engineering technology to isolate and reconstruct a cell's protein trafficking machinery.
          Read More
          A mosquito is shown on human skin.
          FeaturedGenetics
          ·May 29, 2013·3 min read

          Genetic Engineering Alters Mosquitoes’ Sense of Smell

          In one of the first successful attempts at genetically engineering mosquitoes, HHMI researchers have altered the way the insects respond to odors, including the smell of humans and the insect repellant DEET.
          Read More
          Genetics
          ·April 17, 2012·3 min read

          New Genetically Engineered Mice Aid Understanding of Incurable Neuromuscular Disease

          A team of scientists from the University of Missouri created a genetically modified mouse that mimics key features of Charcot-Marie-Tooth...
          Read More
          FeaturedGeneticsNeuroscience
          ·June 30, 2011·3 min read

          Nervous System Stem Cells Can Replace Themselves, Give Rise to Variety of Cell Types, Even Amplify

          Team reconstituted stem cells’ “family tree” A Johns Hopkins team has discovered in young adult mice that a lone brain...
          Read More

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          This shows astrocytes.

          Astrocytes Take the Lead: Hidden Stars of Brain Rhythms Revealed

          This shows a brain and people exercising.

          Mental Health Benefits of Exercise Depend on Context

          This shows neurons and DNA.

          Later-Born Neurons Mature Faster to Keep Networks in Balance

          This shows a brain and exercise symbols.

          Find Exercise You Enjoy: Personality Shapes Fitness Success

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