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gene editing

Featured Genetics Neuroscience Open Neuroscience Articles

·September 25, 2020·5 min read

A Genetic Variant That Protects Against Alzheimer’s Promotes Immune Cell Functions

PLCG2-P522R, a genetic variant that protects against Alzheimer's disease, enhances key functions of immune cells.

This shows a drawing of a fetus attached to a placenta

Featured Genetics Neuroscience

·December 27, 2019·3 min read

Placental protein makes a critical contribution to healthy fetal development

Study reveals how a protein that transports essential amino acids across the placenta plays a role in fetal development. Deficiencies of the SNAT4 protein may result in developmental abnormalities and a higher risk of miscarriage.

Featured Genetics Neuroscience Psychology

·September 23, 2019·4 min read

Gene regulators work together for oversized impact on schizophrenia risk

Using CRISPR to alter the expression of four schizophrenia implicated genes which harbor expression quantitative trait loci, researchers were able to mirror gene expression changes seen in postmortem brains of those suffering from three mental health disorders.

Featured Genetics Neuroscience

·June 12, 2019·7 min read

Using gene editing, neuroscientists develop a new model for autism

Using CRISPR gene editing, researchers introduce the SHANK3 gene variant into macaque monkeys. SHANK3 has previously been linked to autism in humans. The monkeys with the SHANK3 mutations exhibited behavioral traits and brain activity patterns similar to those seen in humans on the autism spectrum, Researchers hope the new model will facilitate new avenues of research for ASD.

This shows a child looking at a DNA double helix

Autism Featured Genetics Neuroscience

·May 24, 2019·4 min read

New approaches to study the genetics of autism may lead to new therapies

Researchers will present their latest findings regarding genes associated with autism spectrum disorder in an upcoming meeting.

Featured Neuroscience

·May 5, 2019·4 min read

New chemical probe for visualizing brain immune cells

The chemical probe CDr20 can label microglia in living cells, researchers report.

Brain Cancer Featured Genetics Neuroscience Open Neuroscience Articles

·April 16, 2019·4 min read

Scientists ‘reverse engineer’ brain cancer cells to find new targets for treatment

Using CRISPR-Cas9 gene editing, researchers identified actionable pathways responsible for the growth of glioblastoma stem cells. By reverse engineering brain cancer cells, multiple potential new targets for cancer treatments have been uncovered.

These are two of the baby clone monkeys.

Featured Genetics Neuroscience Neuroscience Videos Open Neuroscience Articles

·April 11, 2019·5 min read

Gene-edited disease monkeys cloned in China

Researchers in China successfully used CRISPR gene editing to produce five monkey clones from the fibroblasts of a donor monkey with disease phenotypes.

Featured Genetics Neuroscience

·February 25, 2019·2 min read

Manipulating Gene Expression in Neurons with CRISPR

By optimizing neurons with CRISPR gene editing technology, researchers will have new ways to study genetic influences on brain health and disease, a new study reports.

Featured Genetics Neuroscience Open Neuroscience Articles

·February 20, 2019·3 min read

Genetic Mechanism Involved in How Females Inherit Traits Identified

Researchers have identified a specific mechanism involved in how females inherit traits. The findings could help reduce susceptibility to Fragile X and Rett syndrome, the researchers report.

Featured Genetics

·February 18, 2019·6 min read

CRISPR Gene Editing Makes Stem Cells ‘Invisible’ to Immune System

Researchers say the new technique can help prevent transplant rejection.

Autism Featured Genetics Neuroscience Open Neuroscience Articles

·February 12, 2019·3 min read

New Insight into Genetic Mutations Associated with Autism

Using CRISPR gene editing technology, researchers discover increased activity in neurons deficient in the CNTN5 or EHMT2 genes may cause ASD related characteristics in humans.

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gene editing

A Genetic Variant That Protects Against Alzheimer’s Promotes Immune Cell Functions

Placental protein makes a critical contribution to healthy fetal development

Gene regulators work together for oversized impact on schizophrenia risk

Using gene editing, neuroscientists develop a new model for autism

New approaches to study the genetics of autism may lead to new therapies

New chemical probe for visualizing brain immune cells

Scientists ‘reverse engineer’ brain cancer cells to find new targets for treatment

Gene-edited disease monkeys cloned in China

Manipulating Gene Expression in Neurons with CRISPR

Genetic Mechanism Involved in How Females Inherit Traits Identified

CRISPR Gene Editing Makes Stem Cells ‘Invisible’ to Immune System

New Insight into Genetic Mutations Associated with Autism

Immune Cells in the Brain Discovered to Control Puberty and Reproduction

Lifelong Motion Patterns Predict Lifespan

Diverse Biological Roots of Alzheimer’s Revealed

Overlooked Brainstem Pathway Discovered to Control Human Hands

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