Kinase enzymes are essential for neurons to perform autophagy. Researchers found deleting genes that encode kinase NDR1 and NDR2 impairs neuron health and spurs neurodegeneration in both young and old mice.
A new imaging technique captures information about the function and structure of brain tissue at the subcellular level.
In patients with ALS, astrocytes within the brain become pro-inflammatory and tend to lose their protective function, resulting in changes in the ability to uptake glutamate.
Glial cells coordinate immune responses in the gut following infection. Researchers report glial cells could be targets for therapeutics to treat inflammatory bowel disorders.
Researchers reveal how proteins accumulate in the incorrect parts of brain cells in ALS, and demonstrate how it may be possible to reverse the accumulation.
Researchers have identified 27 protein biomarkers that can predict whether a patient with COVID-19 is likely to develop severe coronavirus symptoms.
Researchers have developed a new method to record brain activity at scale. The new technique could help in the development of new neuroprosthetic devices to help amputees and those with movement restricting neurological conditions.
Genetically preventing apoptosis during brain growth allows 'zombie' cells to develop into functioning neurons.
A new, comprehensive database of gene activity in mice, which incorporates ten disease models, could significantly reduce the need for animal testing.
A new collaborative study has helped researchers to uncover some of the earliest molecular events in ALS.
A new study sheds light on how some forms of motor neuron disease begins and progresses at a cellular level.
Researchers provide new insight into the organization of nerve cells within the gut that help control its function.
