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Francis Crick Institute

This shows a cross section of a mouse gut

·October 20, 2021·3 min read

Glial Cells Crucial to Maintaining Healthy Gut Immunity

Glial cells coordinate immune responses in the gut following infection. Researchers report glial cells could be targets for therapeutics to treat inflammatory bowel disorders.

Featured Genetics Neuroscience

·December 3, 2022·3 min read

Genes That Maintain Healthy Neurons Identified

Kinase enzymes are essential for neurons to perform autophagy. Researchers found deleting genes that encode kinase NDR1 and NDR2 impairs neuron health and spurs neurodegeneration in both young and old mice.

Featured Genetics Neurology Neuroscience

·January 19, 2022·6 min read

Astrocyte Studies Reveal Harmful Changes in Amyotrophic Lateral Sclerosis

In patients with ALS, astrocytes within the brain become pro-inflammatory and tend to lose their protective function, resulting in changes in the ability to uptake glutamate.

Featured Neuroscience

·May 19, 2017·4 min read

Understanding the Architecture of Our ‘Second Brain’

Researchers provide new insight into the organization of nerve cells within the gut that help control its function.

Featured Genetics Neurology Neuroscience

·August 11, 2023·6 min read

AI Pinpoints Parkinson’s Subtypes Using Stem Cell Images

Researchers enabled machine learning to accurately predict Parkinson's disease subtypes using stem cell images. This breakthrough showcases computer models classifying four Parkinson’s subtypes, with top accuracies reaching 95%.

This shows cells from the olfactory bulb

Featured Neuroscience Open Neuroscience Articles

·May 25, 2022·4 min read

Scientists Build Subcellular Map of Entire Brain Networks

A new imaging technique captures information about the function and structure of brain tissue at the subcellular level.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·August 6, 2021·5 min read

Key Hallmark of ALS Reversed

Researchers reveal how proteins accumulate in the incorrect parts of brain cells in ALS, and demonstrate how it may be possible to reverse the accumulation.

Featured Neurology Neuroscience

·August 7, 2023·5 min read

COVID Variants Can Affect the Brain in Different Ways

New research found that variants of COVID-19 can affect the brain in different ways and that the blood-brain barrier can be impacted. Scientists exposed brain cells to multiple strains of SARS-CoV-2, including the original wild-type virus, alpha, beta, delta, eta and omicron.

Featured Genetics Neurology Neuroscience Open Neuroscience Articles

·June 28, 2019·6 min read

Gene activity database could spare thousands of mice

A new, comprehensive database of gene activity in mice, which incorporates ten disease models, could significantly reduce the need for animal testing.

Featured Neurology Open Neuroscience Articles

·May 30, 2017·5 min read

Motor Neuron Disease Discovery Offers New Insights into Potential Treatment Targets

A new study sheds light on how some forms of motor neuron disease begins and progresses at a cellular level.

Featured Genetics Neurology Open Neuroscience Articles

·May 25, 2018·5 min read

Researchers Shed New Light on Motor Neuron Death

A new collaborative study has helped researchers to uncover some of the earliest molecular events in ALS.

This shows a brain with a computer chip on top

Featured Neuroscience Open Neuroscience Articles

·March 20, 2020·3 min read

New brain reading technology could help the development of brainwave-controlled devices

Researchers have developed a new method to record brain activity at scale. The new technique could help in the development of new neuroprosthetic devices to help amputees and those with movement restricting neurological conditions.

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