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dendritic spines

·March 8, 2021·4 min read

Watching the Brain Learn

In older mice, adult neurons in the primary visual cortex with an increased number of "silent synapses" and lacking PSD-95, showed the same structural changes only seen previously in younger animals.

This shows dendritic spines on hippocampal neurons

Featured Neuroscience

·October 13, 2020·4 min read

A New Approach to Analyzing the Morphology of Dendritic Spines

A clusterization approach allows researchers to analyze dendritic spines in new ways.

Featured Genetics Neuroscience Open Neuroscience Articles

·March 11, 2020·2 min read

JNK protein triggers neurons to withdraw their synapses when stressed

Using optogenetics to inhibit the JNK protein prevented synapses from shrinking in response to stress.

Featured Genetics Neuroscience Psychology

·October 25, 2019·4 min read

Schizophrenia risk gene linked to cognitive deficits

SETD1A, a gene associated with schizophrenia, stunts the growth and branching of dendrites and reduces the number of dendritic spines. Reinstating the normal expression of SETD1A in mouse models restored working memory function.

Featured Neuroscience Psychology

·October 21, 2019·3 min read

Pregnancy stress triggers immune response that may contribute to postpartum depression

Chronic stress during pregnancy increases neuroinflammation. The immune changes may create circumstances in the brain, which increase susceptibility to postnatal depression.

Featured Neuroscience Open Neuroscience Articles Psychology

·April 11, 2019·3 min read

Ketamine reverses neural changes underlying depression-related behaviors: Mouse study

The formation of prefrontal cortex dendritic spine formation sustains the remission of depressive related symptoms and behaviors following ketamine treatment by restoring lost spines.

Featured Neuroscience Open Neuroscience Articles

·July 5, 2018·5 min read

New Software Designed for Rapid and Automated Identification of Dendritic Spines

Researchers have developed a new machine learning algorithm that can autonomously and efficiently identify dendritic spines with 90% accuracy.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·June 12, 2018·5 min read

Protein’s Role in Mediating Brain’s Response to Stress Identified

Researchers have identified the role Klf9 plays in the brain's response to stress. The study reports elevated levels of the protein were discovered in the hippocampus of women with MDD who faced stressful events.

Featured Neuroscience

·June 10, 2018·4 min read

Thorny Life of New Born Neurons

A new study reports repeated stimulation enlarges dendritic spines, enabling contact with existing neural networks.

Featured Neurology

·October 24, 2017·5 min read

Brain Structure Makes Some Resilient to Alzheimer’s

According to researchers, the size, shape and number of dendritic spines in the brain may determine whether a person develops Alzheimer's disease.

Featured Neurology Open Neuroscience Articles

·October 10, 2017·6 min read

When the Brain’s Wiring Breaks

A new study reveals molecular details of what happens when axons are damaged or completely severed.

Featured Neuroscience Open Neuroscience Articles

·October 9, 2017·3 min read

Human Minibrains Reveal Effects of Psychedelic Substance

A new study reveals psychedelic substances may have a neuroprotective role when it comes to inflammation. Researchers also report psychedelics can alter signaling pathways associated with neuroplasticity.

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