Specific combinations of microorganisms in the gut can worsen symptoms of multiple sclerosis in mouse models of the autoimmune disease.
Anacardic acid, a compound found in cashew shells, promotes the repair of myelin. The findings could have positive implications for the treatment of diseases, such as multiple sclerosis, that are characterized by demyelination.
A global knockout of the thrombin receptor PAR1 accelerates myelin development. The findings could help with the development of treatments for diseases associated with demyelination, like multiple sclerosis.
Ceramide exposure impairs the ability for neurons to make energy by directly damaging mitochondria. Additionally, ceramides force neurons to rapidly uptake glucose in order to provide cellular energy.
Researchers have discovered how the body is able to initiate repair mechanisms which can limit the extent of damage to the myelin sheath. The findings could help with the development of new therapies for multiple sclerosis.
Acrolein, a molecule implicated as a metabolic waste product, could be a potential biomarker for multiple sclerosis, researchers report.
A new study challenges conventional thought on the origins of multiple sclerosis. Researchers say biochemical injury to myelin appears to trigger an immune response that leads to additional damage as a result of inflammation. The new theory challenges the view that MS is primarily at autoimmune disease at origin.
A new study reveals how autophagy in certain immune cells can lead to the immune system attacking the central nervous system. The findings have implications for the treatment of autoimmune diseases, like multiple sclerosis.
Researchers have discovered how TH1 and TH17 immune cells obtain access to neurons in multiple sclerosis.
A new study sheds light on demylination diseases like Multiple Sclerosis. Researchers discovered a blood clotting protein can leak into the central nervous system and prevent myelin production.
Researchers have identified a unique biomarker in the blood of people with Multiple Sclerosis. Using a simple blood test, researchers were able to identify those with MS and discriminate between people at different stages of the disease.
Renewed, thin myelin sheaths are sufficient to help restore nervous system impairments in diseases like multiple sclerosis, a new study in PNAS reports.