A newly developed adeno-associated virus vector can deliver an anti-p Tau antibody directly to the hippocampus, significantly reducing pTau levels associated with CTE. Read More
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Longer career length and playing specific positions put NFL players at greater risk of developing cognitive problems and mental health issues. Playing for 10 or more seasons increased the risks for depression, anxiety, and cognitive impairment twice as much than those who played for a single season. For every five seasons of play, the risks increase 20% for cognitive impairment. Those most at risk are running backs, linebackers and those who played special teams positions. Read More
Sustained hits following one season of playing football are enough to cause structural alterations to the brain. When players sustain a concussion, structural brain integrity decreases, and levels of tau increase. Researchers say, while concussions are a prime concern for those who play football, sustained hits also pose a threat to neurological health. Read More
PET imaging of former NFL players who exhibited cognitive decline and psychiatric symptoms linked to CTE showed higher levels of tau in areas of the brain associated with the neurodegenerative disease. Read More
Researchers say a single season of playing high school football is all it takes to cause microscopic alterations to the structure of the brain. Read More
A new study identifies a genetic mutation that may influence the severity of CTE. Read More
Researchers find evidence of cognitive issues and miRNA biomarkers, indicating brain injuries from concussions or head-to-head contact, in college football players. The findings indicated lasting damage caused by sports related concussions occur earlier than expected. Read More
Researchers report activating microglia may help reduce the imbalance between neuroprotection and neurotoxicity for neurodegenerative diseases. Read More
A new study, which involved a small sample of former professional athletes, found no evidence of early onset dementia. Read More
A new study of football players who were diagnosed with CTE reveals those who started playing tackle football before the age of 12 had earlier onset of emotional and cognitive problems. Read More
Using data from replacement players who entered into the NFL when professionals went on strike in 1987, researchers evaluate player mortality and overall health. The findings, researchers report, may help to make the game safer for current football players. Read More
A new study reveals head impact, not concussion, triggers CTE. The discovery could help with early detection and treatments for the neurodegenerative disorder. Read More
