Researchers use an experimental PET scan tracer to effectively find brain protein deposits specific to CTE in the brain of a retired NFL player.
PET imaging of former NFL players who exhibited cognitive decline and psychiatric symptoms linked to CTE showed higher levels of tau in areas of the brain associated with the neurodegenerative disease.
Researchers report concussion can accelerate Alzheimer's symptoms in people with a genetic risk for the disease.
A newly developed adeno-associated virus vector can deliver an anti-p Tau antibody directly to the hippocampus, significantly reducing pTau levels associated with CTE.
Researchers report a toxic form of tau protein increases following TBI, leading to the development of the same type of mental impairments seen in Alzheimer's patients.
Researchers measure a marker of activated glial cell response in current and former NFL football players who have suffered concussions.
Mislocalization of the TDP-43 protein alters the genetic instructions for UNC13A. The findings provide a potential new therapeutic target for the treatment of ALS and frontotemporal dementia.
Researchers analyze historical records and conclude Henry VIII may have suffered repeated TBIs similar to those experienced by modern football players.
College football players are 5 times more likely to report cognitive impairment, 2.5 times more likely to experience recurrent headaches, and 65% more likely to have cardiovascular problems in their lifetime than their non-football playing peers. Additionally, mortality from brain and other nervous system cancers was 4 times higher in former college football players than the general population.
A new study from researchers at Boston University reports an increase in later life emotional and behavioral problems in people who played youth tackle football before the age of 12.
A new study reports neuroinflammation could have a direct involvement in the development of CTE.
Researchers provide new insights into behavioral problems which occur due to repeated blows to the head.