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CSHL

·March 2, 2026·6 min read

Brain’s Family Tree: A New Theory of Neural Self-Organization

A new theory of brain development suggests that neurons find their place by staying near their relatives, rather than following distant chemical signals.

Brain Cancer Featured Neurology Neuroscience

·December 15, 2025·5 min read

Cancer Disrupts the Brain’s Internal Clock

Breast cancer can rapidly derail the brain’s day-night regulation of stress hormones, even before tumors are detectable. In mice, the disease flattens normal corticosterone rhythms by altering hypothalamic neuron activity, which may worsen outcomes and mimic symptoms often seen in cancer patients, such as insomnia and anxiety.

Neuroscience

·December 1, 2025·5 min read

Singing Mice Reveal How Brains Evolved for Vocal Speech

Alston’s singing mice produce loud, rhythmic songs that scientists can clearly hear, alongside ultrasonic calls used for close-range communication. Researchers discovered that both types of vocalizations are generated through a whistle-like airflow mechanism rather than vibrating vocal cords.

Featured Neuroscience

·October 29, 2025·5 min read

How the Brain’s Ion Gates Open and Close

New research reveals how tiny electrical gates in the brain, known as NMDA receptors, control learning, memory, and neuron survival. Using cryo-electron microscopy, scientists captured atomic-level images showing how a natural neurosteroid, 24S-HC, holds these channels wide open, while a synthetic compound locks them partially shut.

Featured Neuroscience Psychology

·February 14, 2025·4 min read

How Ketamine Binds to Brain Receptors to Alter Mood

New research sheds light on how ketamine affects the brain by targeting a specific NMDA receptor subtype, GluN1-2B-2D. Scientists used electron cryo-microscopy to capture how ketamine binds to this receptor, revealing multiple attachment sites that influence brain activity.

Auditory Neuroscience Featured Neuroscience

·January 30, 2025·4 min read

How the Brain Adapts to New Sensory Contexts

New research reveals how the brain rapidly adapts to sensory changes using a feedback loop between the olfactory cortex and the olfactory bulb. Scientists trained mice to associate rewards with specific sounds and smells, then switched the rules to test their adaptability.

Featured Neuroscience Psychology

·January 6, 2025·4 min read

How the Brain Blends Senses to Understand Social Cues

New research reveals how smell and hearing interact in the brain during maternal behaviors like pup retrieval in mice. Signals from the basal amygdala (BA) merge with auditory inputs in the auditory cortex (AC), influencing responses to social sounds.

Featured Genetics Neuroscience

·November 26, 2024·4 min read

DNA to AI: How Evolution Shapes Smarter Algorithms

A new AI algorithm inspired by the genome’s ability to compress vast information offers insights into brain function and potential tech applications. Researchers found that this algorithm performs tasks like image recognition and video games almost as effectively as fully trained AI networks.

Featured Neurology Neuroscience

·October 17, 2024·4 min read

“Brain on Fire”: When Antibodies Attack the Brain

Anti-NMDAR encephalitis, a rare autoimmune disease, can cause extreme psychiatric symptoms such as hallucinations, paranoia, and memory loss, often mimicking bipolar disorder or schizophrenia. This condition, often affecting women in their 20s to 30s, results from antibodies attacking brain receptors essential for cognition and memory.

Featured Neuroscience Visual Neuroscience

·October 10, 2024·4 min read

Neuroimaging Reveals How OPC Cells Shape Visual Processing

Researchers revealed the intricate role of OPC cells in shaping the brain's neural circuits. Previously known mainly for supporting neuron insulation, OPCs also prune unnecessary synaptic connections, refining the brain’s wiring as we accumulate experiences.

This shows a golden brain on a motherboard.

Featured Neuroscience

·June 20, 2024·5 min read

Brain Inspired AI Learns Like Humans

Today's AI can read, talk, and analyze data but still has critical limitations. NeuroAI researchers designed a new AI model inspired by the human brain's efficiency. This model allows AI neurons to receive feedback and adjust in real time, enhancing learning and memory processes. The innovation could lead to a new generation of more efficient and accessible AI, bringing AI and neuroscience closer together.

Featured Neuroscience Visual Neuroscience

·June 3, 2024·4 min read

Mapping Millions of Brain Connections

Researchers upgraded BARseq to map millions of neurons, enhancing our understanding of brain connections. This advanced technique reveals how losing vision changes the visual cortex, making it more like neighboring brain areas.