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This shows a rendering of an NMDA receptor

·November 2, 2022·3 min read

A New Look at Brain Function and Psychiatric Disorders

Researchers have revealed the 3D structure of NMDA receptor molecules that are critical for brain health. NMDA receptors are believed to contribute to a range of neurological and psychiatric disorders, including schizophrenia, depression, stroke, and Alzheimer's disease. The new model could help with the development of novel treatments for neuropsychiatric disorders.

Featured Genetics Neuroscience

·January 24, 2024·3 min read

T Cells May Be The Living Anti-Aging Elixir

Researchers found that T cells can be genetically reprogrammed to target and eliminate senescent cells, which contribute to aging-related diseases. By using CAR (chimeric antigen receptor) T cells in mice, they achieved significant health improvements including lower body weight, enhanced metabolism, and increased physical activity.

Featured Neurology Neuroscience Neuroscience Videos Open Neuroscience Articles

·April 16, 2020·4 min read

Researchers investigate overactive immune cells as cause of COVID-19 deaths

Study investigates whether overactive immune cells that produce neutrophil extracellular traps (NETs) are responsible for more severe and lethal cases of coronavirus.

Featured Genetics Neuroscience

·November 26, 2024·4 min read

DNA to AI: How Evolution Shapes Smarter Algorithms

A new AI algorithm inspired by the genome’s ability to compress vast information offers insights into brain function and potential tech applications. Researchers found that this algorithm performs tasks like image recognition and video games almost as effectively as fully trained AI networks.

Featured Neurology Neuroscience

·July 22, 2019·3 min read

Quantifying how the brain smells

The olfactory experience is subjective. The perception of odors depends on the context and prior experience of an individual.

Neuroscience

·December 1, 2025·5 min read

Singing Mice Reveal How Brains Evolved for Vocal Speech

Alston’s singing mice produce loud, rhythmic songs that scientists can clearly hear, alongside ultrasonic calls used for close-range communication. Researchers discovered that both types of vocalizations are generated through a whistle-like airflow mechanism rather than vibrating vocal cords.

Featured Neurology Neuroscience

·October 17, 2024·4 min read

“Brain on Fire”: When Antibodies Attack the Brain

Anti-NMDAR encephalitis, a rare autoimmune disease, can cause extreme psychiatric symptoms such as hallucinations, paranoia, and memory loss, often mimicking bipolar disorder or schizophrenia. This condition, often affecting women in their 20s to 30s, results from antibodies attacking brain receptors essential for cognition and memory.

This shows the cluster of neurons activated by FEzf2

Featured Neuroscience

·December 9, 2021·3 min read

Fine-Tuning Motivation in the Brain

Researchers implicate neurons in the anterior insula cortex as a driving force for motivation in the brain, according to a new mouse study.

Featured Neuroscience Psychology

·January 6, 2025·4 min read

How the Brain Blends Senses to Understand Social Cues

New research reveals how smell and hearing interact in the brain during maternal behaviors like pup retrieval in mice. Signals from the basal amygdala (BA) merge with auditory inputs in the auditory cortex (AC), influencing responses to social sounds.

Featured Neuroscience Psychology

·February 14, 2025·4 min read

How Ketamine Binds to Brain Receptors to Alter Mood

New research sheds light on how ketamine affects the brain by targeting a specific NMDA receptor subtype, GluN1-2B-2D. Scientists used electron cryo-microscopy to capture how ketamine binds to this receptor, revealing multiple attachment sites that influence brain activity.

This shows neurons in the basolateral amygdala

Featured Neuroscience

·October 18, 2021·3 min read

Mammalian Motivation Circuits: Maybe They’re Born With It

Researchers have identified a pre-programmed neural circuit in the basolateral amygdala of mice that processes both positive and negative stimuli.

Featured Neuroscience

·May 23, 2024·4 min read

AI Decodes Fruit Fly Vision, Paving Way for Human Insight

Researchers developed an AI model of the fruit fly brain to understand how vision guides behavior. By genetically silencing specific visual neurons and observing changes in behavior, they trained the AI to predict neural activity and behavior accurately. Their findings reveal that multiple neuron combinations, rather than single types, process visual data in a complex "population code." This breakthrough paves the way for future research into the human visual system and related disorders.