Researchers have identified the structural basis for SARS-CoV-2 inhibition by the drug Remdesivir. The findings reveal a potential binding pattern that offers support for the design of new, more efficient, and specific anti-COVID-19 drugs. Read More
Ion channels use a "ball-and-chain" mechanism to help regulate ion flow. Findings confirm a long-standing hypothesis about ion channels and provide key advances in understanding the basic biological processes at work. Read More
A new study questions previous assumption about how Parkinson's disease develops and progresses. Read More
A detailed 3D structure of nicotinic acetylcholine receptors could help pave the way to developing new treatments for nicotine addiction, researchers report. Read More
Researchers from UT Southwestern's Cryo-EM Facility have determined the 3D anatomical structure of the TRPML1 ion channel. The ion channel has been implicated in mucolipidosis type IV, a rare, genetic neurodegenerative disease. Read More
New information about the structure of the TRPA1 protein could help provide new treatments for inflammation induced pain. Read More
