Researchers have uncovered the molecular structure of three major complexes of glutamate receptors in the hippocampus. The findings shed new light on the mechanisms behind memory and learning in the brain.
Researchers have identified the structural basis for SARS-CoV-2 inhibition by the drug Remdesivir. The findings reveal a potential binding pattern that offers support for the design of new, more efficient, and specific anti-COVID-19 drugs.
Ion channels use a "ball-and-chain" mechanism to help regulate ion flow. Findings confirm a long-standing hypothesis about ion channels and provide key advances in understanding the basic biological processes at work.
A new study questions previous assumption about how Parkinson's disease develops and progresses.
A detailed 3D structure of nicotinic acetylcholine receptors could help pave the way to developing new treatments for nicotine addiction, researchers report.
Researchers from UT Southwestern's Cryo-EM Facility have determined the 3D anatomical structure of the TRPML1 ion channel. The ion channel has been implicated in mucolipidosis type IV, a rare, genetic neurodegenerative disease.
New information about the structure of the TRPA1 protein could help provide new treatments for inflammation induced pain.