A mutation in a gene associated with circadian rhythm extends the clock period, causing people to stay up late at night and sleep late in the mornings.
Study reveals how sleep deprivation can greatly affect soldiers on the battlefield.
During wakeful periods, the glymphatic system diverts cerebrospinal fluid to lymph nodes in the neck. The CSF may act as a "fluid clock" that helps initiate the body's infection-fighting capabilities during the day. Astrocytes in the suprachiasmatic nucleus may serve to control CSF through the central nervous system. Communication between astrocytes in different brain regions may optimize the glymphatic system's function as we sleep.
Both food timing and the integrity of the internal clock in the liver altered rhythms of metabolism in mice. Almost half of the rhythmic genes are regulated by both the internal clock and when food is ingested.
Altering the structure of perineuronal nets could be a mechanism that underlies sleep-induced memory changes.
Circadian rhythm disruptions in older men have been linked to an increased risk of developing Parkinson's disease. The findings suggest circadian disruptions may reflect the neurodegenerative processes already affecting the brain's internal clock prior to the diagnosis of Parkinson's. Circadian disruptions, researchers say, could be considered an early warning sign of Parkinson's.
Researchers uncover an intimate connection between methylation and the body's circadian rhythms.
Recovered stroke patients who suffer from sleep-wake disruptions are more likely to experience another stroke, researchers report.
A new study puts into question conventional belief that the eyes communicate with the brain exclusively via one signaling pathway. Researchers have identified a subset of retinal neurons that sends inhibitory signals to the brain. This subset of neurons is also involved in the synchronization of circadian rhythms to light/dark cycles and pupil constriction to bright light intensity.