Latest

choline

·July 24, 2024·9 min read

Neural Vulnerabilities and Resilience in Alzheimer’s Explored

Researchers uncover how specific brain cells and circuits become vulnerable in Alzheimer's disease and identify factors that may promote resilience to cognitive decline. Analyzing gene expression in over 1.3 million cells across multiple brain regions, the study highlights the role of Reelin in neuron protection and choline metabolism in astrocytes for cognitive resilience. These findings pave the way for potential therapeutic targets to sustain cognition and memory amid Alzheimer’s pathology.

Featured Neurology Neuroscience

·January 17, 2023·9 min read

The Effects of Dietary Choline Deficiency on Neurologic and System-Wide Health

Study reveals how dietary choline deficiency adversely affects the body and how it could be a missing piece of the puzzle when it comes to Alzheimer's disease.

Featured Neurology Neuroscience

·December 13, 2022·5 min read

Novel Imaging Marker Reveals Very Early Brain Changes in Alzheimer’s Disease

The integrity of cholinergic pathways may indicate very early changes in the brain associated with Alzheimer's disease.

Featured Neuroscience

·July 28, 2022·4 min read

Study Provides Better Insight Into the Vagus Nerve’s Link to the Brain

Using stimulation, researchers found a direct connection between the vagus nerve and learning centers of the brain. Vagus nerve stimulation, they discovered, increases learning in a healthy nervous system.

Featured Genetics Neuroscience Psychology

·April 7, 2022·6 min read

Human Gene Variant Produces Attention Deficit Disorder-Like Problems in Mice

Mice with the Val89 choline transporter variant had reduced rates of choline uptake and a diminished capacity to sustain acetylcholine production during attention-demanding conditions. The effect led to decreased cognitive performance when the mice were faced with additional challenges.

Featured Neuroscience

·January 3, 2022·5 min read

Choline During Pregnancy Impacts Children’s Sustained Attention

Increased choline consumption during pregnancy was associated with better performance in tasks requiring sustained attention in children aged seven. Researchers found doubling the recommended amount of choline by increasing consumption of nuts, eggs, red meats, and fish during pregnancy had the greatest benefits for the developing fetal brain.

Featured Neuroscience Open Neuroscience Articles

·December 16, 2021·3 min read

Choline Transporter in the Brain Is Necessary for Tuning Out Unneeded Information

The choline transporter protein regulates habituation to smells in fruit fly brains.

Featured Neuroscience Psychology

·July 7, 2021·4 min read

Work Like a Dream: New Anticholinergic Drug Keeps PTSD Flashbacks and Nightmares Away

Trihexyphenidyl, an anticholinergic medication commonly prescribed for Parkinson's symptoms, appears to alleviate negative memory flashbacks and nightmares experienced by those with PTSD.

Featured Genetics Neurology Neuroscience

·March 3, 2021·5 min read

Why the APOE4 Gene Enhances Alzheimer’s Risk

APOE4 affects lipid metabolism, but taking choline supplements may help protect carriers from developing Alzheimer's disease and slow cognitive decline.

Featured Neuroscience Open Neuroscience Articles Psychology

·December 30, 2020·4 min read

Study Delves Into Emotional Wellness in the Human Brain

NAA, a compound in the brain, plays a key role in emotional agency and flexibility in healthy people.

This is a graphic abstract from the study

Featured Neuroscience

·June 2, 2020·3 min read

Some people are easily addicted to drugs, but others are not

Dopamine D2 receptor overexpression in cholinergic interneurons of the nucleus accumbens may explain why some are more prone to cocaine addiction than others.

Featured Genetics Neuroscience

·March 30, 2020·5 min read

Alcohol consumption by fathers before conception could impact brain development

Male alcohol consumption before conception was linked to significant deficits in their offspring's brain development, specifically within the neocortex. For mothers-to-be who drink alcohol, the negative outcomes of prenatal alcohol exposure on fetal brain development can be reduced with choline supplementation.

1 2 3 … 5

choline

Neural Vulnerabilities and Resilience in Alzheimer’s Explored

The Effects of Dietary Choline Deficiency on Neurologic and System-Wide Health

Novel Imaging Marker Reveals Very Early Brain Changes in Alzheimer’s Disease

Study Provides Better Insight Into the Vagus Nerve’s Link to the Brain

Human Gene Variant Produces Attention Deficit Disorder-Like Problems in Mice

Choline During Pregnancy Impacts Children’s Sustained Attention

Choline Transporter in the Brain Is Necessary for Tuning Out Unneeded Information

Work Like a Dream: New Anticholinergic Drug Keeps PTSD Flashbacks and Nightmares Away

Why the APOE4 Gene Enhances Alzheimer’s Risk

Study Delves Into Emotional Wellness in the Human Brain

Some people are easily addicted to drugs, but others are not

Alcohol consumption by fathers before conception could impact brain development

Keto Diet May Ease Multiple Sclerosis Symptoms

Toddlers Learn Best After Experiencing Impossible Events

Omega-3 and 6 Linked to Lower Cancer Risk

Lower Blood Sugar Diet Linked to Slower Brain Aging

Subscribe