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choline

Featured Genetics Neuroscience Psychology

·April 7, 2022·6 min read

Human Gene Variant Produces Attention Deficit Disorder-Like Problems in Mice

Mice with the Val89 choline transporter variant had reduced rates of choline uptake and a diminished capacity to sustain acetylcholine production during attention-demanding conditions. The effect led to decreased cognitive performance when the mice were faced with additional challenges.

Featured Neuroscience

·January 3, 2022·5 min read

Choline During Pregnancy Impacts Children’s Sustained Attention

Increased choline consumption during pregnancy was associated with better performance in tasks requiring sustained attention in children aged seven. Researchers found doubling the recommended amount of choline by increasing consumption of nuts, eggs, red meats, and fish during pregnancy had the greatest benefits for the developing fetal brain.

Featured Neuroscience Open Neuroscience Articles

·December 16, 2021·3 min read

Choline Transporter in the Brain Is Necessary for Tuning Out Unneeded Information

The choline transporter protein regulates habituation to smells in fruit fly brains.

Featured Neuroscience Psychology

·July 7, 2021·4 min read

Work Like a Dream: New Anticholinergic Drug Keeps PTSD Flashbacks and Nightmares Away

Trihexyphenidyl, an anticholinergic medication commonly prescribed for Parkinson's symptoms, appears to alleviate negative memory flashbacks and nightmares experienced by those with PTSD.

Featured Genetics Neurology Neuroscience

·March 3, 2021·5 min read

Why the APOE4 Gene Enhances Alzheimer’s Risk

APOE4 affects lipid metabolism, but taking choline supplements may help protect carriers from developing Alzheimer's disease and slow cognitive decline.

Featured Neuroscience Open Neuroscience Articles Psychology

·December 30, 2020·4 min read

Study Delves Into Emotional Wellness in the Human Brain

NAA, a compound in the brain, plays a key role in emotional agency and flexibility in healthy people.

This is a graphic abstract from the study

Featured Neuroscience

·June 2, 2020·3 min read

Some people are easily addicted to drugs, but others are not

Dopamine D2 receptor overexpression in cholinergic interneurons of the nucleus accumbens may explain why some are more prone to cocaine addiction than others.

Featured Genetics Neuroscience

·March 30, 2020·5 min read

Alcohol consumption by fathers before conception could impact brain development

Male alcohol consumption before conception was linked to significant deficits in their offspring's brain development, specifically within the neocortex. For mothers-to-be who drink alcohol, the negative outcomes of prenatal alcohol exposure on fetal brain development can be reduced with choline supplementation.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·November 12, 2019·3 min read

Small RNAs link immune system and brain cells

Findings show sex-specific baizes in gene expression changes and demonstrate cellular control mechanisms based on microRNA change. The study sheds new light on genetic and neurological changes associated with schizophrenia and bipolar disorder.

Featured Neurology Neuroscience Open Neuroscience Articles

·September 27, 2019·8 min read

Common nutrient supplement choline may hold the answers to combating Alzheimer’s

Taking dietary choline supplements may help to protect the brain from Alzheimer's disease. Choline reduces the activation of microglia which, when overactivated, contribute to neuroinflammation and apoptosis associated with Alzheimer's. Choline also helps block the production of amyloid plaques.

Featured Neuroscience Open Neuroscience Articles

·September 1, 2019·3 min read

Vegan and Plant-Based Diets Worsen Brain Health

Eating a vegan or plant-based diet can be bad for your brain health, especially if you already have a low choline intake, researchers report.

Featured Genetics Neuroscience

·August 15, 2019·3 min read

Moderate to heavy drinking during pregnancy alters genes in newborns and mothers

POMC, a gene which regulates the stress response system, and PER2, a gene associated with circadian regulation, are altered in women who drank moderate-to-high amounts of alcohol during pregnancy and their newborns.

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