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cholesterol

·November 11, 2024·6 min read

Fluctuating Cholesterol Linked to Higher Dementia Risk

Older adults with significant fluctuations in cholesterol levels are at increased risk for dementia and cognitive decline, even without medication changes. Researchers studied nearly 10,000 older adults, tracking their cholesterol levels and cognitive function over six years. High variability in total and LDL ("bad") cholesterol was associated with a 60% increase in dementia and 23% increase in cognitive decline.

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·October 11, 2024·4 min read

HDL Cholesterol Quality, Not Quantity, Linked to Alzheimer’s Risk

Higher levels of HDL, the so-called "good cholesterol," may not protect against Alzheimer's in postmenopausal women, with the risk potentially tied to the quality, not quantity, of HDL particles. A new study shows that larger HDL particles, which increase during menopause, lose efficiency in supporting cognitive health.

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Featured Neurology Neuroscience

·November 30, 2023·5 min read

High ‘Good Cholesterol’ Linked to Dementia Risk

A new study found that abnormally high levels of HDL-C (high-density lipoprotein cholesterol), often referred to as 'good cholesterol', may increase the risk of dementia in older adults. This large-scale study, part of the ASPREE project, observed over 18,668 participants, noting that those with very high HDL-C levels had a 27% higher risk of dementia.

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·September 29, 2022·5 min read

How Long Older Adults Will Live Comes Down to 17 Often Surprising Factors

Researchers have designed a new model of life expectancy that's based less on disease diagnosis, and more on other factors including cholesterol levels and lifestyle.

Featured Neuroscience Open Neuroscience Articles

·May 14, 2022·5 min read

Drinker’s Sex Plus Brewing Method May Be Key to Coffee’s Link to Raised Cholesterol

The sex of the drinker in addition to the brewing method may explain coffee's link to increased cholesterol. Drinking 3-5 cups of espresso per day increased serum total cholesterol, especially in males.

Featured Neuroscience Psychology

·May 13, 2022·5 min read

Links Connecting Stress, Depression and Heart Disease Risk Found

Mouse study reveals how depression and chronic stress can have an impact on cholesterol-lowering medications and influence the risk of heart disease.

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Featured Neurology Neuroscience

·March 23, 2022·3 min read

Lipid and Glucose Levels at Age 35 Associated With Alzheimer’s Disease

Low HDL and high triglyceride levels in the blood at 35 were associated with an increased risk of developing Alzheimer's disease later in life. Additionally, higher glucose levels between 51 and 60 were linked to a higher risk of Alzheimer's.

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Featured Neurology Neuroscience

·March 12, 2022·4 min read

Brain Cell Insight Could Lead to New Treatments for Neurological-Based Diseases

Study reports oligodendrocytes in the brain are distinct from oligodendrocytes in the central nervous system due to their metabolic processes. The findings may shed new light on neurological and autoimmune dysfunction in multiple sclerosis and other neurodegenerative disorders.

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Featured Neurology Neuroscience

·January 19, 2022·5 min read

Cholesterol Buildup in Brain Presents New Target to Reduce Dementia Risk From Stroke

Cyclodextrin, an FDA-approved drug, reduced cholesterol accumulation from broken down brain cells and inflammation in animal models. The findings point to a potential new therapy to reduce dementia following a stroke.

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Autism Featured Neuroscience Open Neuroscience Articles

·December 7, 2021·3 min read

Youth With Autism Should Be Screened for Abnormal Cholesterol Levels

Researchers found those on the autism spectrum with low high-density lipoprotein cholesterol or decreased ApoA1 levels had lower adaptive functioning than others with ASD.

Featured Neurology Neuroscience

·November 10, 2021·4 min read

Strategies for the Regeneration of Myelin

Cholesterol synthesis in nerve cells ensures the replenishment of newly myelin-forming cells. The findings could provide new treatment options for the treatment of disorders associated with myelin loss, such as multiple sclerosis.

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·September 15, 2021·3 min read

Stem Cells Model Genetic Risk for Developing Alzheimer’s Disease

Stem cell study reveals astrocytes carrying the Alzheimer's associated APOE4 gene release more cholesterol than those carrying the APOE3 gene. Findings shed light on how different versions of the APOE gene in astrocytes influence amyloid-beta production and how the oversupply of cholesterol associated with APOE4 astrocytes may promote amyloid-beta formation in Alzheimer's patients.