Fenofibrate, an FDA-approved drug commonly used to treat high cholesterol, activated support cells around sensory neurons in mouse models of spinal cord injury, helping them regrow twice as fast as a placebo.
At the site of injury, nerves release a protein called CXCL12 which attracts growing nerve fibers and keeps them trapped in place. This prevents the nerve fibers from growing in the correct direction to bridge the injury site.
IgA cells that originate in the gut play a role appear to have neuroprotective properties against diseases associated with neuroinflammation, such as meningitis.
By fusing a cytokine to a blood protein, researchers have developed a new therapy to help treat multiple sclerosis.
Identical twins were more likely to have similar sun-seeking behaviors than non-identical twins, suggesting genetics play a key role in sun-seeking behaviors. Researchers identified five genes associated with sun-seeking behavior, some of which have previously been associated with behavioral traits linked to risk-taking and addiction.
Reviewing data from past pandemics, researchers suggest some of those exposed to COVID-19 could have an increased risk of developing neurological and mental health disorders in the long term. Acute viral infections can result in encephalopathy, psychosis, depression, demyelination disorders, and problems with neuromuscular function.
Enhancing mitochondrial transportation and cellular energetics could help promote regeneration and function following spinal cord injury.