The release of 2-AG, a natural endocannabinoid that is suggested to be the brain's equivalent to THC, dampens down seizure activity but increases post-seizure oxygen deprivation in the brain.
Brain and fetal development damage caused by exposure to CBD and THC are very similar defects seen in fetal alcohol syndrome.
Mice exposed to dough containing THC were less active and had lower body temperature after consumption. The effects were more pronounced in males than females.
Researchers have identified the structure of the human type 2 cannabinoid receptor. The findings, researchers say, can help in the development of new treatments for inflammatory and neurodegenerative diseases.
Researchers shed light on the endocannabinoid system and report how cannabis is helping to provide relief to many with medical problems.
A new study reveals how dangerous inflammations in the brain are caused during the aging process. Researchers say failure with the CB1 to control activity of immune cells may result in chronic neuroinflammation. They say it may be possible to break this vicious cycle in the future with drugs that contain THC, which is a powerful CB1 receptor activator.
Researchers report low doses of THC can help restore memory and reverse some of the effects of brain aging in mice. The findings could open new avenues for treating dementia and other neurodegenerative diseases.
Researchers report deficiencies of natural cannabinoids could result in a predisposition for developing depression and PTSD. Boosting the system could help in treating stress related disorders.
A new study suggests developing new therapeutics that use cannabinoid receptors to treat chronic pain.