CA3

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CA3

Electrophysiology Featured Neuroscience Psychology

·February 19, 2020

Altered potassium levels in neurons may cause mood swings in bipolar disorder

Increased potassium currents were responsible for hyperactivity of CA3 neurons. When exposed to potassium channel blockers, the hyperactivity disappeared. However, when exposed to lithium, the drug not only reversed hyperactivity but reduced potassium currents at the same time. The findings strengthen the case that potassium currents play a role in bipolar disorder. Read More

Image shows brain cells from a mouse cortex.

Featured Genetics Neurology Open Neuroscience Articles

·October 10, 2016

Alzheimer’s Could be Treated With Gene Therapy: Mouse Study

Researchers report they have successfully prevented the development of Alzheimer's in mice by using gene therapy delivered by a virus to the brain. Read More

Featured Genetics Neuroscience

·September 2, 2017

Bone Derived Hormone Reverses Age Related Memory Loss: Mouse Study

Researchers report boosting levels of osteocalcin in the blood may help reverse age related memory loss in mice. Read More

Featured Neuroscience Neuroscience Videos

·September 23, 2015

Brain Circuit Critical in Forming Episodic Memory Identified

Researchers identify a neural circuit that connects the hippocampus and the entorhinal cortex, which is responsible for encoding episodic memory. Read More

Image shows a brain and marijuana leaves.

Featured Neuroscience Open Neuroscience Articles

·September 23, 2017

Breaking Memory Circuits With Marijuana

New research reveals the dynamics of neural circuits under the influence of cannabinoids. Read More

This is a drawing of the hippocampus with CA3, CA1 and the DG labeled.

Electrophysiology Featured Neuroscience

·March 30, 2015

Building Block for Memory and Learning Identified

Researchers discover a key receptor which is responsible for activating opposing forms of plasticity in the hippocampus. Read More

Image shows the CA1 area of the hippocampus highlighted in a mouse brain.

Featured Neuroscience

·January 18, 2016

Cellular Diversity in the Hippocampus

Researchers have discovered an unexpected diversity within CA1 pyramidal neurons in the hippocampus. Read More

Featured Genetics Neuroscience Psychology

·January 8, 2019

Childhood Stress Affects Behavior of Offspring: Mouse Study

Researchers report on the epigenetic effect of early life stress. In a new study, researchers reveal mice who experienced stress in the first few weeks of life showed deterioration in memory, learning and maternal behaviors. Behavioral changes were seen in their later offspring, regardless of sex. Read More

Image shows a diagram of the hippocampus.

Featured Neurology

·October 16, 2017

Dietary Supplement Dampens Brain Hyperexcitability Seen in Epilepsy

Researchers were able to dampen hyperexcitability associated with seizure disorders in rodent models by inducing biochemical alterations with glucosamine, a dietary supplement. Read More

The image shows a rat holding a hershey's kiss.

Featured Neuroscience

·February 27, 2013

Discovery About Animal Memory Opens Doors to Research on Memory Impairment Diseases

A new study offers evidence of source memory in nonhuman animals. Read More

Electrophysiology Featured Neuroscience

·October 8, 2012

Discovery of Gatekeeper Nerve Cells Explains the Effect of Nicotine on Learning and Memory

Researchers discovered a new group of nerve cells that regulate processes of learning and memory. These cells act as gatekeepers and carry a receptor for nicotine, which can help explain our ability to remember and sort information. The newly discovered gatekeeper nerve cells, also called OLM-alpha2 cells, provide an explanation to how the flow of information is controlled in the hippocampus. Read More

Autism Featured Neuroscience Open Neuroscience Articles

·June 4, 2019

Exercise fine-tunes brain’s connections, eases autism spectrum disorder in mouse model

Participating in exercise improved synaptic pruning in mouse models of autism. The study also found microglia dependant synaptic pruning is impaired by maternal inflammation, which has been previously connected to the development of ASD. Read More

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