CA3

Latest

CA3

Electrophysiology Featured Neuroscience Psychology

·February 19, 2020

Altered potassium levels in neurons may cause mood swings in bipolar disorder

Increased potassium currents were responsible for hyperactivity of CA3 neurons. When exposed to potassium channel blockers, the hyperactivity disappeared. However, when exposed to lithium, the drug not only reversed hyperactivity but reduced potassium currents at the same time. The findings strengthen the case that potassium currents play a role in bipolar disorder. Read More

This shows a brain and some waves drawn beneath it

Featured Neurology Neuroscience Open Neuroscience Articles

·November 19, 2019

Predicting Alzheimer’s disease-like memory loss before it strikes

Sharp-wave ripple activity in the brain may be an early biomarker for Alzheimer's disease before cognitive impairment begins. Read More

Featured Neurology Neuroscience

·October 1, 2019

Study provides possible explanation of how a seizure is able to spread through the brain

A new study implicated interneurons and pyramidal cells in the ability of a seizure to spread through the brain. Read More

Autism Featured Neuroscience Open Neuroscience Articles

·June 4, 2019

Exercise fine-tunes brain’s connections, eases autism spectrum disorder in mouse model

Participating in exercise improved synaptic pruning in mouse models of autism. The study also found microglia dependant synaptic pruning is impaired by maternal inflammation, which has been previously connected to the development of ASD. Read More

A detailed drawing of the hippocampal formation is shown.

Electrophysiology Featured Neuroscience

·March 27, 2019

Quick thinking? It’s all down to timing

A pairing of presynaptic and postsynaptic activity in a population of hippocampal neurons can reduce the required number of synaptic plasticity evoking events. When spikes occur within ten milliseconds of each other, synapses strengthen for up to four hours. Read More

Featured Neuroscience Psychology

·February 25, 2019

High Fructose Corn Syrup Consumption Linked to Bipolar Like Behaviors: Adolescent Rat Study

Researchers report adolescent rats exposed to high fructose corn syrup in their diets were more prone to experience symptoms associated with bipolar disorder. Read More

Featured Neuroscience

·January 21, 2019

Unexpected Link Between Feeding and Memory Brain Areas Discovered

A new study reveals how NCOR1/2 regulates memory involving a newly identified circuit between the lateral hypothalamus and hippocampus. Researchers believe the findings could have implications for future studies related to ASD and neurodegenerative diseases. Read More

Featured Genetics Neuroscience Psychology

·January 8, 2019

Childhood Stress Affects Behavior of Offspring: Mouse Study

Researchers report on the epigenetic effect of early life stress. In a new study, researchers reveal mice who experienced stress in the first few weeks of life showed deterioration in memory, learning and maternal behaviors. Behavioral changes were seen in their later offspring, regardless of sex. Read More

Featured Neuroscience

·October 14, 2018

Previous Motherhood Could Affect Hormone Therapy’s Ability to Prevent Memory Loss

A new study reports mother rats who received hormone replacement therapy responded worse to memory and spatial learning tasks than those who had not given birth. Researchers suggest a woman's reproductive history could impact how the brain responds to hormones later in life. Read More

Featured Neuroscience

·June 7, 2018

Maps Made of Nerve Cells

Researchers have created a new model that may help explain how the brain stores memories of tangible events. The new model explains how neural activity in the hippocampus can help map space, time and context in episodic memories. Read More

Featured Neuroscience

·May 10, 2018

Targeting Receptor Related to Serotonin May Boost Memory Formation

Columbia University researchers reveal targeting a specific serotonin receptor can help to boost memory formation. The study reports targeting 5-HT4 receptors could help improve cognitive impairment. Read More

Featured Genetics Neurology Neuroscience Psychology

·May 3, 2018

Interconnected Cells in a Dish Let Researchers Study Brain Disease

Using stem cells to generate a partial model of the brain, researchers discover how communication between neurons is altered in those with Schizophrenia. Read More

1 2 3 4