Drugs that quell brain inflammation reverse dementia
Older mice given anti-inflammatory medication were better able to learn new tasks and became almost as adept at learning as mice half their age.... Read More...
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Drugs that quell brain inflammation reverse dementia
A synthesized small-molecule drug blocks the TGF-beta receptor in astrocytes and traverses the blood-brain barrier in mice. When administered, the drug lowered receptor activity to that seen in younger mice and reduced inflammation. The aged mice were able to navigate mazes and learn spatial tasks as well as younger mice.... Read More...
Ultrasound method restores dopaminergic pathway in brain at Parkinson’s early stages
Using transcranial focused ultrasound in combination with injectable microbubbles, researchers open a pathway through the blood-brain barrier. The technique allows drugs to penetrate the brain and trigger therapeutic effects for those with neurodegenerative diseases.... Read More...
Scientists recreate blood-brain barrier defect outside the body
Using induced pluripotent stem cells derived from patients with neurodegenerative disorders, researcher recreated the blood-brain barrier inside Organ-Chips. ... Read More...
Cannabidiol could help deliver medications to the brain
Cannabidiol may be able to bypass the blood-brain barrier to effectively deliver medications directly to the brain.... Read More...
Breaks in the Blood-Brain Barrier Can Cause Brains to Get Old Before Their Time
A new study reports damage to the blood-brain barrier can cause age related cognitive decline, and sheds light on how we could reverse the aging process in the brain.... Read More...
Blood-Brain Barrier Breakdown an Early Driver of Dementia
A new study reports leaky capillaries in the brain may be an early sign of Alzheimer's disease as it can signal cognitive impairment prior to the buildup of proteins associated with the neurodegenerative disease.... Read More...
Scorpion Venom to Shuttle Drugs Into the Brain
Researchers detail how cholortoxin, a peptide in scorpion venom, can cross the blood-brain barrier for drug delivery.... Read More...
More Immune Cells in Brains of Those with Schizophrenia
A new study reports some people with schizophrenia have increased numbers of immune cells in their brains. Researchers say the immune cells may be producing inflammatory signals in those with the condition. ... Read More...
A Safe and Non-Invasive Way to Open the Blood-Brain Barrier in Alzheimer’s Patients
Researchers use focused ultrasound to safely and non-invasively open the blood-brain barrier in Alzheimer's patients.... Read More...
Switching Brain Circuits On and Off Without Surgery
Researchers have developed a new, non surgical method to manipulate brain circuitry. The technique uses sound waves in combination with small bubble injections into the blood stream that temporarily opens the blood-brain barrier. ... Read More...
Tiny Particles Could Help Fight Brain Cancer
Researchers at MIT have developed a new drug delivering nanoparticle that is able to cross the blood-brain barrier. The nanoparticles carry two different drugs that can help shrink tumors and prevent them from growing back.... Read More...