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BBB

Image of amyloid plaques in Alzheimer's brain tissue.

·September 18, 2015·4 min read

A Major Breakthrough in Understanding of Alzheimer’s Disease Reported

A new study sheds light onto a fundamental mechanism underlying the development of Alzheimer's disease. Researchers believe the findings could lead to new forms of therapy for those living with the disease.

Featured Neuroscience Open Neuroscience Articles

·November 8, 2017·4 min read

A Recipe to Make a Human Blood-Brain Barrier

Researchers have defined a process that can help to create more realistic human blood-brain barriers in a dish.

Featured Neurology Open Neuroscience Articles

·August 26, 2018·3 min read

A Safe and Non-Invasive Way to Open the Blood-Brain Barrier in Alzheimer’s Patients

Researchers use focused ultrasound to safely and non-invasively open the blood-brain barrier in Alzheimer's patients.

Featured Neuroscience

·September 21, 2020·5 min read

Advancing Understanding of Blood-Brain Barrier Health

Study reveals the important role astrocytes play in maintaining blood-brain barrier health.

Image shows a diagram of how the immunotherapy can help treat alzheimer's by bypassing the BBB.

Featured Neurology Open Neuroscience Articles

·January 16, 2017·4 min read

Antibody Therapy Creates New Opportunities For Treating Brain Diseases

Researchers have developed a new antibody design that can increase the uptake of antibodies to the brain by almost a 100 fold.

Image shows a diagram explaining how amitriptyline allows drugs to pass the bbb.

Featured Neurology Neuroscience

·April 27, 2017·4 min read

Antidepressants May Enhance Drug Delivery to Brain

A new study reports an antidepressant temporarily inhibits the blood-brain barrier, allowing drugs to enter the brain. The findings could have implications for treating neurological diseases from ALS to epilepsy.

Featured Genetics Neurology Neuroscience

·April 29, 2020·4 min read

APOE4 triggers early breakdowns in the blood-brain barrier

APOE4, a gene implicated as a risk factor for Alzheimer's disease, triggers leaks in the blood-brain barrier. The damage to capillaries APOE4 causes correlates with increased levels of cyclophilin, a protein that causes the inflammation that is a signature of early Alzheimer's.

Featured Neurology Neuroscience

·February 15, 2018·4 min read

Atlas of Brain Blood Vessels Provides Fresh Clues to Brain Diseases

Researchers have mapped cells that form the brain's blood vessels and blood brain barrier.

Featured Neurology Neuroscience

·January 14, 2019·4 min read

Blood-Brain Barrier Breakdown an Early Driver of Dementia

A new study reports leaky capillaries in the brain may be an early sign of Alzheimer's disease as it can signal cognitive impairment prior to the buildup of proteins associated with the neurodegenerative disease.

Featured Neuroscience

·December 7, 2016·5 min read

Blood-Brain Barrier on a Chip Sheds New Light on ‘Silent Killer’

A new blood-brain barrier on a chip system is being used to study neuroinflammation, researchers report.

Image shows a researcher looking at a brain scan.

Featured Neurology Neuroscience Neuroscience Videos

·November 10, 2015·3 min read

Blood-Brain Barrier Opened Non-Invasively to Deliver Chemotherapy

Researchers have successfully used focused ultrasound to non-invasively penetrate the blood-brain barrier and deliver chemotherapy to a patient with brain cancer.