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·February 6, 2021·5 min read

Critical Flaw Found in Lab Models of the Human Blood-Brain Barrier

Human brain endothelial cells used to generate lab models of the human blood-brain barrier were missing several key proteins found in natural endothelial cells. The cells had more in common with epithelial, a type of cell not normally found in the brain. The findings put into question over a decade worth of lab-based research on the BBB.

Featured Genetics Neurology Neuroscience

·November 22, 2022·4 min read

Gene-Delivering Viruses Reach the Brain in Step Toward Gene Therapy for Neurological Diseases

Researchers have developed a family of adeno-associated viral vectors (AAVs) that are able to cross the blood-brain barrier to deliver gene therapies directly to the brain.

Featured Neurology Open Neuroscience Articles

·August 26, 2018·3 min read

A Safe and Non-Invasive Way to Open the Blood-Brain Barrier in Alzheimer’s Patients

Researchers use focused ultrasound to safely and non-invasively open the blood-brain barrier in Alzheimer's patients.

Featured Neurology

·November 15, 2017·4 min read

Controller Developed to Open the Blood-Brain Barrier With Precision

A new system offers a safer, finer degree of control for opening the blood-brain barrier for drug delivery.

Featured Neuroscience

·February 16, 2016·6 min read

Study Visualizes How Toxoplasma Gondii Crosses the Blood-Brain Barrier

Researchers have discovered how the parasite Toxoplasma gondii is able to cross the blood-brain barrier.

Brain Cancer Featured Open Neuroscience Articles

·February 24, 2016·6 min read

Laser Technology Opens Blood-Brain Barrier to Chemotherapy

Researchers have successfully bypassed the blood-brain barrier using a laser probe to help deliver chemotherapy drugs to glioblastoma patients.

Featured Neuroscience Open Neuroscience Articles Psychology

·September 14, 2018·4 min read

More Immune Cells in Brains of Those with Schizophrenia

A new study reports some people with schizophrenia have increased numbers of immune cells in their brains. Researchers say the immune cells may be producing inflammatory signals in those with the condition.

Brain Cancer Featured Neurology

·October 20, 2016·5 min read

Scientists Build a Better Cancer Drug to Pass Through Blood-Brain Barrier

By altering DON, an anti-cancer drug cultivated from bacteria originally found in Peruvian soil over 70 years ago, scientists believe they have made a safer and more tolerable form of the drug.

Featured Genetics Neuroscience Open Neuroscience Articles Psychology

·October 10, 2017·4 min read

Major Breakthrough Identifies Mechanism for Development of Schizophrenia

A new study sheds light on a potential mechanism for the development of schizophrenia. Researchers believe blood vessel abnormalities could play a significant role in the development of the psychiatric disorder.

Image shows a researcher looking at a brain scan.

Featured Neurology Neuroscience Neuroscience Videos

·November 10, 2015·3 min read

Blood-Brain Barrier Opened Non-Invasively to Deliver Chemotherapy

Researchers have successfully used focused ultrasound to non-invasively penetrate the blood-brain barrier and deliver chemotherapy to a patient with brain cancer.