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Featured Genetics Neurology Neuroscience

·November 25, 2024·4 min read

New Platform Overcomes Blood-Brain Barrier for Drug Delivery

Researchers have developed a breakthrough system to deliver large therapeutic molecules into the brain, overcoming the challenges of the blood-brain barrier.

Featured Neuroscience

·June 3, 2024·4 min read

Could Your Brain Have Its Own Microbiome?

Recent research suggests the brain might host its own microbiome, challenging the long-held belief that it is a sterile organ. Studies have found bacterial and fungal genetic material in brain tissues, particularly in those with Alzheimer’s. The brain microbiome could be linked to diseases, offering potential new treatment avenues. However, much remains unknown about how microbes enter and affect the brain.

Brain Cancer Featured Neurology Neuroscience

·May 6, 2024·6 min read

Nanoparticles Penetrate Blood-Brain Barrier to Treat Cancer

Researchers developed a novel nanoparticle that can cross the blood-brain barrier to target both primary breast tumors and brain metastases simultaneously. This dual-action approach utilizes a biodegradable polymer loaded with two prodrugs targeting cancer cell mitochondria.

Featured Neuroscience

·September 26, 2023·3 min read

Probing E-Cig and Alcohol’s Joint Assault on the Blood-Brain Barrier

E-cigarettes, popular among teens, have been linked to increased alcohol and drug consumption. Now, with NIH funding, researchers seeks to understand the effects of combining e-cigarettes and alcohol on our brain's protective layer: the blood brain barrier.

Featured Neurology Neuroscience

·February 27, 2023·3 min read

Researchers Detail Changes in the Blood-Brain Barrier Related to Alzheimer’s Disease

In those with Alzheimer's disease, the choroid plexus becomes enlarged and has increased accumulation of abnormal inflammatory signatures.

Featured Neurology Neuroscience

·December 17, 2022·5 min read

Why Does the Alzheimer’s Brain Become Insulin-Resistant?

Insulin binding receptors are predominantly located in the microvessels within the blood-brain barrier. In patients with Alzheimer's, the abundance of these receptors is decreased. This decrease could lead to the loss of insulin response in the Alzheimer's brain.

Featured Genetics Neurology Neuroscience

·November 22, 2022·4 min read

Gene-Delivering Viruses Reach the Brain in Step Toward Gene Therapy for Neurological Diseases

Researchers have developed a family of adeno-associated viral vectors (AAVs) that are able to cross the blood-brain barrier to deliver gene therapies directly to the brain.

Brain Cancer Featured Neuroscience

·June 1, 2022·5 min read

Engineers Develop Nanoparticles That Cross the Blood-Brain Barrier

Researchers have developed drug-carrying nanoparticles that cross the blood-brain barrier, allowing for more effective delivery to the brain than conventional medications. The nanoparticles can get into tumors and kill glioblastoma brain cancer cells.